Home » Integrin alpha 4 beta 7/LPAM-1 » Integrin alpha 4 beta 7/LPAM-1 Antibodies » Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [mFluor Violet 500 SE]
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Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
Hu117
Clonality
Monoclonal
Host
Human
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB10078U-100UG
Alexa Fluor 405
FAB10078V-100UG
Alexa Fluor 488
FAB10078G-100UG
Alexa Fluor 532
FAB10078X
Alexa Fluor 594
FAB10078T-100UG
Alexa Fluor 647
FAB10078R-100UG
Alexa Fluor 700
FAB10078N-100UG
Alexa Fluor 750
FAB10078S-100UG
Allophycocyanin
FAB10078A
Allophycocyanin/Cy7
FAB10078APCCY7
Biotin
FAB10078B
CoraFluor 1
FAB10078CL1
DyLight 350
FAB10078D
DyLight 405
FAB10078E
DyLight 488
FAB10078K
DyLight 550
FAB10078L
DyLight 594
FAB10078M
DyLight 650
FAB10078W
DyLight 680
FAB10078Y
DyLight 755
FAB10078Z
FITC
FAB10078F
HRP
FAB10078H
Janelia Fluor 525
FAB10078JF525
Janelia Fluor 549
FAB10078I
Janelia Fluor 585
FAB10078JF585
Janelia Fluor 635
FAB10078JF635
Janelia Fluor 646
FAB10078J
Janelia Fluor 669
FAB10078JF669
PE/Atto594
FAB10078PEATT594
PE/Cy5.5
FAB10078PECY55
PE/Cy7
FAB10078PECY7
PerCP
FAB10078C
Phycoerythrin
FAB10078P-100
Unconjugated
MAB10078-100
mFluor Violet 450 SE
FAB10078MFV450
mFluor Violet 610 SE
FAB10078MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10078-100
Carrier Free
MAB10078-100
Carrier Free
MAB10078-SP
Carrier Free
FAB10078V-100UG
Carrier Free
FAB10078U-100UG
Carrier Free
FAB10078T-100UG
Carrier Free
FAB10078S-100UG
Carrier Free
FAB10078R-100UG
Carrier Free
FAB10078N-100UG
Carrier Free
FAB10078G-100UG
Carrier Free
FAB10078P-100
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Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [mFluor Violet 500 SE] Summary

Additional Information
Recombinant Monoclonal Antibody For Research Use Only
Immunogen
Human Integrin alpha 4 beta 7/LPAM‑1
Specificity
Detects human Integrin alpha 4 beta 7/LPAM‑1 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Vedolizumab. This product is for research use only.
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [mFluor Violet 500 SE]

  • 269C wild type
  • CD49 antigen-like family member D
  • CD49d antigen
  • CD49d
  • CD49d/beta7
  • CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor
  • IA4
  • Integrin alpha 4 beta 7
  • integrin alpha 4
  • integrin alpha-4 subunit
  • integrin alpha-4
  • Integrin alpha-IV
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
  • LPAM1
  • LPAM-1
  • MGC90518
  • very late activation protein 4 receptor, alpha 4 subunit
  • VLA-4 subunit alpha

Background

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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