Home » Histone Deacetylase 4/HDAC4 » Histone Deacetylase 4/HDAC4 Antibodies » Histone Deacetylase 4/HDAC4 [p Ser632] Antibody [CoraFluor™ 1]
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Histone Deacetylase 4/HDAC4 [p Ser632] Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-54636AF350
Alexa Fluor 405
NBP2-54636AF405
Alexa Fluor 488
NBP2-54636AF488
Alexa Fluor 532
NBP2-54636AF532
Alexa Fluor 594
NBP2-54636AF594
Alexa Fluor 647
NBP2-54636AF647
Alexa Fluor 700
NBP2-54636AF700
Alexa Fluor 750
NBP2-54636AF750
Biotin
NBP2-54636B
DyLight 350
NBP2-54636UV
DyLight 405
NBP2-54636V
DyLight 488
NBP2-54636G
DyLight 550
NBP2-54636R
DyLight 594
NBP2-54636DL594
DyLight 650
NBP2-54636C
DyLight 680
NBP2-54636FR
DyLight 755
NBP2-54636IR
FITC
NBP2-54636F
HRP
NBP2-54636H
Janelia Fluor 525
NBP2-54636JF525
Janelia Fluor 549
NBP2-54636JF549
Janelia Fluor 585
NBP2-54636JF585
Janelia Fluor 635
NBP2-54636JF635
Janelia Fluor 646
NBP2-54636JF646
Janelia Fluor 669
NBP2-54636JF669
PerCP
NBP2-54636PCP
Unconjugated
NBP2-54636-0.05mg
mFluor Violet 450 SE
NBP2-54636MFV450
mFluor Violet 500 SE
NBP2-54636MFV500
mFluor Violet 610 SE
NBP2-54636MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-54636-0.05mg
BSA Free
NBP2-54636
BSA Free
NBP2-54636-0.05mg
BSA Free
NBP2-54636-0.025mg
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Histone Deacetylase 4/HDAC4 [p Ser632] Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
HDAC4 (Ab-632) antibody was raised against a peptide sequence around aa. 630~634 (A-Q-S-S-P) derived from Human HDAC4.
Modification
p Ser632
Specificity
This antibody detects endogenous level of total Histone Deacetylase 4/HDAC4 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HDAC4
Purity
Epitope affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Epitope affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Histone Deacetylase 4/HDAC4 [p Ser632] Antibody [CoraFluor™ 1]

  • HA6116
  • HD4EC 3.5.1.98
  • HDAC4
  • HDAC-A
  • HDACABDMR
  • Histone Deacetylase 4
  • histone deacetylase A
  • KIAA0288AHO3

Background

Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs and there are currently 2 classes. Class I proteins are related to Rpd3 and members of class II resemble Hda1p.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Histone Deacetylase 4/HDAC4 [p Ser632] Antibody [CoraFluor™ 1]
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Bioinformatics

Gene Symbol HDAC4