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DEP-1/CD148 Antibody (261922) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
261922
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

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DEP-1/CD148 Antibody (261922) [mFluor Violet 610 SE] Summary

Immunogen
E. coli-derived recombinant human DEP‑1/CD148
Arg997-Ala1337
Accession # Q12913
Specificity
Detects human DEP‑1/CD148.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PTPRJ
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DEP-1/CD148 Antibody (261922) [mFluor Violet 610 SE]

  • CD148 antigen
  • CD148
  • Density-enhanced phosphatase 1
  • DEP1
  • DEP-1
  • DEP1EC 3.1.3.48
  • HPTP eta
  • HPTPeta
  • HPTP-eta
  • human density enhanced phosphatase-1
  • protein tyrosine phosphatase, receptor type, J polypeptide
  • protein tyrosine phosphatase, receptor type, J
  • Protein-tyrosine phosphatase eta
  • Protein-tyrosine phosphatase receptor type J
  • PTPRJ
  • receptor-type tyrosine-protein phosphatase eta
  • R-PTP-ETA
  • R-PTP-J
  • SCC1
  • susceptibility to colon cancer 1, mouse, homolog of

Background

PTPRJ is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PTPRJ