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CXCR2/IL-8RB Antibody (HC2) - Chimeric - Azide and BSA Free

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Immunocytochemistry/Immunofluorescence: CXCR2/IL-8RB Antibody (HC2) - Chimeric [NBP3-12005] - Immunofluorescence analysis of paraformaldehyde fixed human peripheral blood leukocytes on Shi-fix(TM) coverslips stained with the chimeric rabbit IgG version of HC2 (NBP3-12005) at 10 ug/ml for 1h followed by Alexa Fluor(R) 488 secondary antibody (2 ug/ml), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom NBP3-12005, DAPI, merged channels and an isotype control. The isotype control was an unknown specificity antibody followed by staining with Alexa Fluor(R) 488 secondary antibody.
Immunocytochemistry/ Immunofluorescence: CXCR2/IL-8RB Antibody (HC2) - Chimeric [NBP3-12005] - Immunofluorescence analysis of paraformaldehyde fixed human peripheral blood leukocytes on Shi-fix(TM) coverslips stained ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, ICC/IF
Clone
HC2
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-12005AF350
Alexa Fluor 405
NBP3-12005AF405
Alexa Fluor 488
NBP3-12005AF488
Alexa Fluor 532
NBP3-12005AF532
Alexa Fluor 594
NBP3-12005AF594
Alexa Fluor 647
NBP3-12005AF647
Alexa Fluor 700
NBP3-12005AF700
Alexa Fluor 750
NBP3-12005AF750
Allophycocyanin
NBP3-12005APC
Biotin
NBP3-12005B
CoraFluor 1
NBP3-12005CL1
DyLight 350
NBP3-12005UV
DyLight 405
NBP3-12005V
DyLight 488
NBP3-12005G
DyLight 550
NBP3-12005R
DyLight 594
NBP3-12005DL594
DyLight 650
NBP3-12005C
DyLight 680
NBP3-12005FR
DyLight 755
NBP3-12005IR
FITC
NBP3-12005F
HRP
NBP3-12005H
Janelia Fluor 525
NBP3-12005JF525
Janelia Fluor 549
NBP3-12005JF549
Janelia Fluor 646
NBP3-12005JF646
Janelia Fluor 669
NBP3-12005JF669
PE
NBP3-12005PE
PerCP
NBP3-12005PCP
mFluor Violet 450 SE
NBP3-12005MFV450
mFluor Violet 500 SE
NBP3-12005MFV500
mFluor Violet 610 SE
NBP3-12005MFV610
View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP3-12005-0.025mg
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CXCR2/IL-8RB Antibody (HC2) - Chimeric - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was raised by immunizing mice with human IL-8 (interleukin-8) receptor, type B.
Specificity
HC2 recognizes human C-X-C chemokine receptor type 2, (CXCR2). CD182 is a 360 amino acid multipass membrane glcycoprotein and is expressed by neutrophils and monocytes, as well as by some subsets of T cells and endothelial cells.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
CXCR2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
Application Notes
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Packaging, Storage & Formulations

Storage
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Buffer
PBS
Preservative
0.02% Proclin 300
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CXCR2/IL-8RB Antibody (HC2) - Chimeric - Azide and BSA Free

  • CD182 antigen
  • CD182
  • CDw128b
  • chemokine (C-X-C motif) receptor 2
  • chemokine (CXC) receptor 2
  • CMKAR2
  • C-X-C chemokine receptor type 2
  • CXCR2 gene for IL8 receptor type B
  • CXCR2
  • CXC-R2
  • CXCR-2
  • GRO/MGSA receptor
  • High affinity interleukin-8 receptor B
  • IL-8 RB
  • IL-8 receptor type 2
  • IL-8R B
  • IL8R2
  • IL8RA
  • IL8RB
  • interleukin 8 receptor B
  • interleukin 8 receptor type 2
  • interleukin-8 receptor type B

Background

Chemokine (Chemoattractant Cytokines) are small peptides that are potent activators and chemo-attractants for leukocyte subpopulations and other non-hemopoietic cells. Chemokine receptors (CXCR) belong to the super-family of G protein-coupled receptors (GPCR), which regulate the trafficking and activation of leukocytes, and operate as co-receptors in the entry of HIV-1 and proliferation and migration of immature neurons, glia and their precursors. Furthermore, chemokine receptors participate in the etiology and progression of various brain disorders, including AIDS dementia, neuro-inflammatory disease and neuroplasia, making them important potential therapeutic targets in these cases several subtypes of CXCR have been characterized. Activation of na

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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M6000B
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Bioinformatics

Gene Symbol CXCR2