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Mouse CXCL2/MIP-2 Quantikine ELISA Kit, 2 Plate

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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse CXCL2/MIP-2 Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse MIP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MIP-2 levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse MIP-2 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse MIP-2 accurately. Results obtained using natural mouse MIP-2 ...showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse MIP-2.
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Specificity
Natural and recombinant mouse MIP-2
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Cxcl2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MM200.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CXCL2/MIP-2 Quantikine ELISA Kit, 2 Plate

  • chemokine (C-X-C motif) ligand 2
  • CINC-2a
  • CINC3
  • CINC-3
  • C-X-C Motif Chemokine 2
  • CXCL2
  • GRO beta
  • GRO2 oncogene
  • GRO2
  • GROB
  • Gro-beta
  • Growth-regulated protein beta
  • Macrophage inflammatory protein 2-alpha
  • melanoma growth stimulatory activity beta
  • MGSA beta
  • MGSA-b
  • MGSA-beta
  • MIP2
  • MIP-2
  • MIP2A
  • MIP-2a
  • MIP2-alpha
  • SCYB2

Background

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL2/GRO beta/MIP-2/CINC-3 (MM200)(176)

We have publications tested in 2 confirmed species: Mouse, Rat.


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Mouse
(175)
Rat
(1)
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Showing Publications 1 - 10 of 176. Show All 176 Publications.
Publications using MM200 Applications Species
Lei, Z;Krishnamachary, B;Khan, NZ;Ji, Y;Li, Y;Li, H;Brunner, K;Faden, AI;Jones, JW;Wu, J; Spinal cord injury disrupts plasma extracellular vesicles cargoes leading to neuroinflammation in the brain and neurological dysfunction in aged male mice Brain, behavior, and immunity 2024-07-08 [PMID: 38986724] (Mouse) Mouse
Silva, IS;Almeida, AD;Lima Filho, ACM;Fernandes-Braga, W;Barra, A;Oliveira, HMC;Cassali, GD;Capettini, LSA;Menezes, GB;Alvarez-Leite, JI;Leite, MF;Klein, A; Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation Scientific reports 2023-12-07 [PMID: 38062077] (Mouse) Mouse
Jung, SH;Chung, KS;Na, CS;Ahn, HS;Shin, YK;Lee, KT; Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel Particulate Matter Nutrients 2023-10-29 [PMID: 37960252] (Mouse) Mouse
Lê, HG;Kang, JM;Võ, TC;Yoo, WG;Na, BK; Naegleria fowleri Extracellular Vesicles Induce Proinflammatory Immune Responses in BV-2 Microglial Cells International journal of molecular sciences 2023-09-03 [PMID: 37686429] (Mouse) Mouse
Pham, HTT;Magez, S;Choi, B;Baatar, B;Jung, J;Radwanska, M; Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis Nature communications 2023-09-05 [PMID: 37669943] (Mouse) Mouse
Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q; LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis Cell reports 2023-08-11 [PMID: 37573508] (Mouse) Mouse
Fei, X;Huang, J;Li, F;Wang, Y;Shao, Z;Dong, L;Wu, Y;Li, B;Zhang, X;Lv, B;Zhao, Y;Weng, Q;Chen, K;Zhang, M;Yang, S;Zhang, C;Zhang, M;Li, W;Ying, S;Sun, Q;Chen, Z;Shen, H; The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-?B Cell reports 2023-06-01 [PMID: 37267109] (Mouse) Mouse
Lei, Z;Krishnamachary, B;Ritzel, RM;Khan, NZ;Li, Y;Li, H;Brunner, K;Faden, AI;Wu, J; Age-related changes in plasma extracellular vesicles influence neuroinflammation in the brain and neurological outcome after traumatic spinal cord injury Research square 2023-04-17 [PMID: 37131758] (Mouse) Mouse
S Luo, C Liao, L Zhang, C Ling, X Zhang, P Xie, G Su, Z Chen, L Zhang, T Lai, J Tang METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling Cell Reports, 2023-03-14;42(3):112259. 2023-03-14 [PMID: 36920907] (Mouse) Mouse
DW Chen, T Kang, XZ Xu, WJ Xia, X Ye, YB Wu, YR Xu, J Liu, H Ren, J Deng, YK Chen, HQ Ding, M Aslam, WM Zelek, BP Morgan, R Kapur, S Santoso, YS Fu Mechanism and intervention of murine transfusion-related acute lung injury caused by anti-CD36 antibodies JCI Insight, 2023-03-22;0(0):. 2023-03-22 [PMID: 36809299] (Mouse) Mouse
Show All 176 Publications.

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Bioinformatics

Gene Symbol Cxcl2