Myeloperoxidase/MPO Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily. MPO is synthesized as a preproprotein that undergoes proteolytic processing to generate a disulfide-linked heterodimer of the N-terminal beta -subunit (12 kDa) and C-terminal alpha subunit (60 kDa). Active MPO is a tetramer of two beta -subunits and two alpha -subunits that are also disulfide-linked through the two alpha -subunits. MPO is stored in granules and is an abundant protein in neutrophils and monocytes. MPO is released upon activation to catalyze the formation of powerful oxidants such as hypochlorous acid, which kills microbes. Unprocessed pro-MPO can also be released. Mouse MPO shares 87% amino acid sequence identity with that of human MPO.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 7 confirmed species: Human, Mouse, Rat, Hamster, Primate, Transgenic Mouse, Xenograft.

We have publications tested in 12 applications: ELISA Capture, ELISA Development, Flow Cytometry, Functional Assay, ICC, ICC/IF, IHC, IHC-Fr, IHC-P, Immunocytochemistry, Immunohistochemistry, Western Blot.

Showing Publications 1 - 10 of 167. Show All 167 Publications. Collapse Publications.

Publications using AF3667	Applications	Species
Kikuchi, K;Kazuma, S;Yamakage, M; Recombinant thrombomodulin and recombinant antithrombin attenuate pulmonary endothelial glycocalyx degradation and neutrophil extracellular trap formation in ventilator-induced lung injury in the context of endotoxemia Respiratory research 2024-09-03 [PMID: 39227918] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Turkkahraman, H;Flanagan, S;Zhu, T;Akel, N;Marino, S;Ortega-Gonzalez, D;Yuan, X;Bellido, T; Sclerostin antibody corrects periodontal disease in type 2 diabetic mice JCI insight 2024-07-18 [PMID: 39171525] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Wang, L;Huang, FY;Dai, SZ;Fu, Y;Zhou, X;Wang, CC;Tan, GH;Li, Q; Progesterone modulates the immune microenvironment to suppress ovalbumin-induced airway inflammation by inhibiting NETosis Scientific reports 2024-07-26 [PMID: 39060348] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Rosenzweig, N;Kleemann, KL;Rust, T;Carpenter, M;Grucci, M;Aronchik, M;Brouwer, N;Valenbreder, I;Cooper-Hohn, J;Iyer, M;Krishnan, RK;Sivanathan, KN;Brandão, W;Yahya, T;Durao, A;Yin, Z;Chadarevian, JP;Properzi, MJ;Nowarski, R;Davtyan, H;Weiner, HL;Blurton-Jones, M;Yang, HS;Eggen, BJL;Sperling, RA;Butovsky, O; Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease Nature medicine 2024-07-03 [PMID: 38961225] (Flow Cytometry, Human, Mouse)	Flow Cytometry	Human, Mouse
Donahue, KL;Watkoske, HR;Kadiyala, P;Du, W;Brown, K;Scales, MK;Elhossiny, AM;Espinoza, CE;Lasse Opsahl, EL;Griffith, BD;Wen, Y;Sun, L;Velez-Delgado, A;Renollet, NM;Morales, J;Nedzesky, NM;Baliira, RK;Menjivar, RE;Medina-Cabrera, PI;Rao, A;Allen, B;Shi, J;Frankel, TL;Carpenter, ES;Bednar, F;Zhang, Y;Pasca di Magliano, M; Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth Cancer discovery 2024-07-03 [PMID: 38958646] (Immunohistochemistry, Transgenic Mouse)	Immunohistochemistry	Transgenic Mouse
Barbu, E;Mihaila, AC;Gan, AM;Ciortan, L;Macarie, RD;Tucureanu, MM;Filippi, A;Stoenescu, AI;Petrea, SV;Simionescu, M;Balanescu, SM;Butoi, E; The Elevated Inflammatory Status of Neutrophils Is Related to In-Hospital Complications in Patients with Acute Coronary Syndrome and Has Important Prognosis Value for Diabetic Patients International journal of molecular sciences 2024-05-08 [PMID: 38791147] (Western Blot, Immunocytochemistry, Human)	Western Blot, Immunocytochemistry	Human
Shad, A;Rewell, SSJ;Macowan, M;Gandasasmita, N;Wang, J;Chen, K;Marsland, B;O'Brien, TJ;Li, J;Semple, BD; Modelling lung infection with Klebsiella pneumoniae after murine traumatic brain injury Journal of neuroinflammation 2024-05-08 [PMID: 38720343] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Su, Q;Su, C;Zhang, Y;Guo, Y;Liu, Y;Liu, Y;Yong, VW;Xue, M; Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice International immunopharmacology 2024-04-01 [PMID: 38565042] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Abraham, MJ;Goncalves, C;McCallum, P;Gupta, V;Preston, SEJ;Huang, F;Chou, H;Gagnon, N;Johnson, NA;Miller, WH;Mann, KK;Del Rincon, SV; Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments Cell & bioscience 2024-02-04 [PMID: 38311785] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Wilkening, RV;Langouët-Astrié, C;Severn, MM;Federle, MJ;Horswill, AR; Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model Cell reports 2023-10-26 [PMID: 37889753] (IHC, Mouse)	IHC	Mouse
Hutka, B;Várallyay, A;László, SB;Tóth, AS;Scheich, B;Paku, S;Vörös, I;Pós, Z;Varga, ZV;Norman, DD;Balogh, A;Benyó, Z;Tigyi, G;Gyires, K;Zádori, ZS; A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy Acta pharmacologica Sinica 2023-10-10 [PMID: 37816857] (Western Blot, IHC, Mouse)	Western Blot, IHC	Mouse
Shi, G;Liu, L;Cao, Y;Ma, G;Zhu, Y;Xu, J;Zhang, X;Li, T;Mi, L;Jia, H;Zhang, Y;Liu, X;Zhou, Y;Li, S;Yang, G;Liu, X;Chen, F;Wang, B;Deng, Q;Zhang, S;Zhang, J; Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1?/ASK1/JNK signaling pathway in mice with traumatic brain injury Journal of neuroinflammation 2023-09-30 [PMID: 37777772] (IHC, Mouse)	IHC	Mouse
Cao, L;Ma, L;Zhao, J;Wang, X;Fang, X;Li, W;Qi, Y;Tang, Y;Liu, J;Peng, S;Yang, L;Zhou, L;Li, L;Hu, X;Ji, Y;Hou, Y;Zhao, Y;Zhang, X;Zhao, YY;Zhao, Y;Wei, Y;Malik, AB;Saiyin, H;Xu, J; An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo eLife 2023-09-20 [PMID: 37728612] (IHC, Human)	IHC	Human
Hao Zhang, Dan Wu, Yanghanzhao Wang, Kefang Guo, Charles B. Spencer, Lilibeth Ortoga et al. METTL3-mediated N6-methyladenosine exacerbates ferroptosis via m6A-IGF2BP2-dependent mitochondrial metabolic reprogramming in sepsis-induced acute lung injury Clin Transl Med 9/15/2023 [PMID: 37715457]
Hernandez Pichardo, A;Wilm, B;Liptrott, NJ;Murray, P; Intravenous Administration of Human Umbilical Cord Mesenchymal Stromal Cells Leads to an Inflammatory Response in the Lung Stem cells international 2023-09-05 [PMID: 37705699] (IHC, Human)	IHC	Human
Mei Yang, Xinmiao Zhou, Stuart W.A. Pearce, Zhisheng Yang, Qishan Chen, Kaiyuan Niu et al. Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice Arteriosclerosis, Thrombosis, and Vascular Biology 8/17/2023 [PMID: 37589142]
Ma T, Tang Y, Wang T et al. Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII(hi) neutrophils Signal Transduction and Targeted Therapy 8/11/2023 [PMID: 37563136]
Ma T, Tang Y, Wang T et al. Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII(hi) neutrophils Signal Transduction and Targeted Therapy 2023-08-11 [PMID: 37563136]
Wu, H;Guo, C;Liu, Z;Cai, J;Wang, C;Yi, H;Sanyal, A;Puri, P;Zhou, H;Wang, XY; Neutrophils exacerbate acetaminophen-induced liver injury by producing cytotoxic interferon-? International immunopharmacology 2023-08-02 [PMID: 37541108] (IHC, Mouse)	IHC	Mouse
Le, PM;Pal-Ghosh, S;Menko, AS;Stepp, MA; Immune Cells Localize to Sites of Corneal Erosions in C57BL/6 Mice Biomolecules 2023-06-29 [PMID: 37509096] (IHC, Mouse)	IHC	Mouse
Perico, L;Morigi, M;Pezzotta, A;Locatelli, M;Imberti, B;Corna, D;Cerullo, D;Benigni, A;Remuzzi, G; SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling Scientific reports 2023-07-14 [PMID: 37452090] (IHC, Transgenic Mouse)	IHC	Transgenic Mouse
Ana Raquel Maceiras, Diogo Silvério, Rute Gonçalves, Marcos S. Cardoso, Margarida Saraiva Infection with hypervirulent Mycobacterium tuberculosis triggers emergency myelopoiesis but not trained immunity Frontiers in Immunology 6/13/2023 [PMID: 37383236]
Shiratori-Aso, S;Nakazawa, D;Kudo, T;Kanda, M;Ueda, Y;Watanabe-Kusunoki, K;Nishio, S;Iwasaki, S;Tsuji, T;Masuda, S;Tomaru, U;Ishizu, A;Atsumi, T; CD47 blockade ameliorates autoimmune vasculitis via efferocytosis of neutrophil extracellular traps JCI insight 2023-08-08 [PMID: 37368493] (IHC, Mouse)	IHC	Mouse
Chen Li, Tianli Chen, Jialiang Liu, Yue Wang, Chunhuan Zhang, Lu Guo et al. FGF19‐Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer Advanced Science 8/1/2023 [PMID: 37345586]
Huerga Encabo, H;Aramburu, IV;Garcia-Albornoz, M;Piganeau, M;Wood, H;Song, A;Ferrelli, A;Sharma, A;Minutti, CM;Domart, MC;Papazoglou, D;Gurashi, K;Llorian Sopena, M;Goldstone, R;Fallesen, T;Wang, Q;Ariza-McNaughton, L;Wiseman, DH;Batta, K;Gupta, R;Papayannopoulos, V;Bonnet, D; Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils Cell stem cell 2023-06-01 [PMID: 37267914] (ICC, IHC, Mouse)	ICC, IHC	Mouse
Sung, PS;Sun, CP;Tao, MH;Hsieh, SL; Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc EMBO molecular medicine 2023-05-22 [PMID: 37211986] (Immunohistochemistry, Immunocytochemistry, Human, Mouse)	Immunohistochemistry, Immunocytochemistry	Human, Mouse
Yiyao Cao, Mingming Shi, Liang Liu, Yan Zuo, Haoran Jia, Xiaobin Min et al. Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/IRE1 alpha pathway after traumatic brain injury in mice Frontiers in Immunology 4/14/2023 [PMID: 37143681]
Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros et al. C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps Journal of Clinical Investigation 6/15/2023 [PMID: 37104043]
N Boonpraman, S Yoon, CY Kim, JS Moon, SS Yi NOX4 as a critical effector mediating neuroinflammatory cytokines, myeloperoxidase and osteopontin, specifically in astrocytes in the hippocampus in Parkinson's disease Redox Biology, 2023-04-10;62(0):102698. 2023-04-10 [PMID: 37058998] (ICC, Western Blot, Mouse)	ICC, Western Blot	Mouse
FP Veras, GF Gomes, BMS Silva, DB Caetité, CJLR Almeida, CMS Silva, AH Schneider, ES Corneo, CS Bonilha, SS Batah, R Martins, E Arruda, AT Fabro, JC Alves-Filh, TM Cunha, FQ Cunha Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model Respiratory Research, 2023-03-02;24(1):66. 3/2/2023 [PMID: 36864506]
X Peng, Y Li, W Zhao, S Yang, J Huang, Y Chen, Y Wang, Z Gong, X Chen, C Yu, S Cai, H Zhao Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma International immunopharmacology, 2023-02-22;117(0):109719. 2023-02-22 [PMID: 36827917] (IHC, Mouse)	IHC	Mouse
Julia Elrod, Moritz Lenz, Antonia Kiwit, Lina Armbrust, Lavinia Schönfeld, Konrad Reinshagen et al. Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns Frontiers in Immunology 2/7/2023 [PMID: 36825027]
K Sivaraman, S Wrenger, B Liu, D Schaudien, C Hesse, G Gomez-Mari, S Perez-Luz, K Sewald, D DeLuca, MJ Wurm, P Pino, T Welte, B Martinez-D, S Janciauski Mice inflammatory responses to inhaled aerosolized LPS: effects of various forms of human alpha1-antitrypsin Journal of leukocyte biology, 2023-01-10;113(1):58-70. 2023-01-10 [PMID: 36822165] (IHC, Mouse)	IHC	Mouse
Tracy W Liu, Seth T Gammon, Ping Yang, Wencai Ma, Jing Wang, David Piwnica-Worms Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma Journal for ImmunoTherapy of Cancer 2/17/2023 [PMID: 36805920]
Min Kook Lee, Hyo Dam Kim, Suk Hee Lee, Jin Hyup Lee Curcumin Ameliorates Particulate Matter-Induced Pulmonary Injury through Bimodal Regulation of Macrophage Inflammation via NF-kappa B and Nrf2 International Journal of Molecular Sciences 1/17/2023 [PMID: 36768180]
Briana N. James, Cynthia Weigel, Christopher D. Green, Ryan D. R. Brown, Elisa N. D. Palladino, Anuj Tharakan et al. Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice The FASEB Journal 3/1/2023 [PMID: 36753412]
D Kucsera, VE Tóth, NV Sayour, T Kovács, TG Gergely, M Ruppert, T Radovits, A Fábián, A Kovács, B Merkely, P Ferdinandy, ZV Varga IL-1beta neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH Scientific Reports, 2023-01-07;13(1):356. 2023-01-07 [PMID: 36611037] (IHC, Mouse)	IHC	Mouse
Ali A. Zarban, Hiba Chaudhry, Davide Maselli, Xenia Kodji, Joao de Sousa Valente, Justin Joachim et al. Enhancing Techniques for Determining Inflammatory Edema Formation and Neutrophil Accumulation in Murine Skin JID Innovations 1/1/2023 [PMID: 36561914]
Michael T. Bounajem, Frederik Denorme, John L. Rustad, Robert A. Campbell, Ramesh Grandhi Investigation of Neutrophil Extracellular Traps as Potential Mediators in the Pathogenesis of Non-Acute Subdural Hematomas: A Pilot Study Diagnostics (Basel) 11/24/2022 [PMID: 36552941]
Morten F. Gjerstorff, Sofie Traynor, Odd L. Gammelgaard, Simone Johansen, Christina B. Pedersen, Henrik J. Ditzel et al. PDX Models: A Versatile Tool for Studying the Role of Myeloid-Derived Suppressor Cells in Breast Cancer Cancers (Basel) 12/13/2022 [PMID: 36551639]
K Wang, Y Liao, X Li, R Wang, Z Zeng, M Cheng, L Gao, D Xu, F Wen, T Wang, J Chen Inhibition of neutrophil elastase prevents cigarette smoke exposure-induced formation of neutrophil extracellular traps and improves lung function in a mouse model of chronic obstructive pulmonary disease International immunopharmacology, 2022-12-07;114(0):109537. 2022-12-07 [PMID: 36495695] (ICC, Human)	ICC	Human
J Huang, H Tao, PG Yancey, Z Leuthner, LS May-Zhang, JY Jung, Y Zhang, L Ding, V Amarnath, D Liu, S Collins, SS Davies, MF Linton Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance Molecular Metabolism, 2022-12-05;67(0):101651. 2022-12-05 [PMID: 36481344] (IHC, Mouse)	IHC	Mouse
J Zeller, KS Cheung Tun, TL Nero, JD McFadyen, G Krippner, B Bogner, S Kreuzaler, J Kiefer, VK Horner, D Braig, H Danish, S Baratchi, M Fricke, X Wang, MG Kather, B Kammerer, KJ Woollard, P Sharma, CJ Morton, G Pietersz, MW Parker, K Peter, SU Eisenhardt A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein Embo Molecular Medicine, 2022-12-05;0(0):e16236. 2022-12-05 [PMID: 36468184] (ICC, Human)	ICC	Human
Yin Li, Qinyi Jiang, Xiaohua Zhou, Mengyuan Wu, Jian Chen, Hao Liu et al. A prospective marker for the prediction of postoperative deep venous thrombosis: Neutrophil extracellular traps Frontiers in Cell and Developmental Biology 11/16/2022 [PMID: 36467414]
Iker Valle Aramburu, Dennis Hoving, Spyros I. Vernardis, Martha C.F. Tin, Marianna Ioannou, Mia I. Temkin et al. Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia Immunity 12/13/2022 [PMID: 36462503]
GJ Pir, A Parray, R Ayadathil, SV Pananchikk, FA Mir, I Muhammad, A Abubakar, N Amir, S Hussain, KH Haroon, A Muhammad, Y Imam, SN Patro, N Akhtar, A Zakaria, S Kamran Platelet-Neutrophil Association in NETs-Rich Areas in the Retrieved AIS Patient Thrombi International Journal of Molecular Sciences, 2022-11-21;23(22):. 2022-11-21 [PMID: 36430952] (IHC, Human)	IHC	Human
Kentaro Nakata, Mikio Okazaki, Tomohisa Sakaue, Rie Kinoshita, Yuhei Komoda, Dai Shimizu et al. Functional Blockage of S100A8/A9 Ameliorates Ischemia–Reperfusion Injury in the Lung Bioengineering (Basel) 11/10/2022 [PMID: 36354584]
J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer Cancer Research, 2022-11-15;0(0):OF1-OF14. 2022-11-15 [PMID: 36306422] (ICC, IHC, Human, Mouse)	ICC, IHC	Human, Mouse
Lifei Hou, Richard A. Voit, Miho Shibamura-Fujiogi, Sophia Koutsogiannaki, Yunan Li, Yue Chen et al. CD11c regulates neutrophil maturation Blood Advances 4/11/2023 [PMID: 36306384]
Hsuan-An Chen, Yu-Jui Ho, Riccardo Mezzadra, Jose M. Adrover, Ryan Smolkin, Changyu Zhu et al. Senescence rewires microenvironment sensing to facilitate anti-tumor immunity Cancer Discovery 2/6/2023 [PMID: 36302222]
Kirsti Hornigold, Julia Y. Chu, Stephen A. Chetwynd, Polly A. Machin, Laraine Crossland, Chiara Pantarelli et al. Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses Frontiers in Immunology 8/24/2022 [PMID: 36090969]
PS Sung, YC Peng, SP Yang, CH Chiu, SL Hsieh CLEC5A is critical in Pseudomonas aeruginosa-induced acute lung injury JCI Insight, 2022-09-01;0(0):. 2022-09-01 [PMID: 36048544] (IHC, Mouse)	IHC	Mouse
Mengdi Qu, Zhaoyuan Chen, Zhiyun Qiu, Ke Nan, Yanghanzhao Wang, Yuxin Shi et al. Neutrophil extracellular traps-triggered impaired autophagic flux via METTL3 underlies sepsis-associated acute lung injury Cell Death Discovery 8/27/2022 [PMID: 36030287]
H Li, C Qiao, L Zhao, Q Jing, D Xue, Y Zhang Epigallocatechin-3-gallate reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis Journal of leukocyte biology, 2022-08-19;0(0):. 2022-08-19 [PMID: 35983712] (ICC, Human)	ICC	Human
Yamamoto Y, Kadoya K, Terkawi MA et al. Neutrophils delay repair process in Wallerian degeneration by releasing NETs outside the parenchyma Life science alliance 10/1/2022 [PMID: 35961782]
F Gao, Y Niu, L Sun, W Li, H Xia, Y Zhang, S Geng, Z Guo, H Lin, G Du Integrating network pharmacology and transcriptomic validation to investigate the efficacy and mechanism of Mufangji decoction preventing lung cancer Journal of ethnopharmacology, 2022-07-30;0(0):115573. 2022-07-30 [PMID: 35917893] (ICC/IF, Mouse)	ICC/IF	Mouse
Pierre Janssen, Irene Tosi, Alexandre Hego, Pauline Maréchal, Thomas Marichal, Coraline Radermecker Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity Frontiers in Immunology 7/13/2022 [PMID: 35911691]
A Gupta, K Singh, S Fatima, S Ambreen, S Zimmermann, R Younis, S Krishnan, R Rana, I Gadi, C Schwab, R Biemann, K Shahzad, V Rani, S Ali, PR Mertens, S Kohli, B Isermann Neutrophil Extracellular Traps Promote NLRP3 Inflammasome Activation and Glomerular Endothelial Dysfunction in Diabetic Kidney Disease Nutrients, 2022-07-20;14(14):. 2022-07-20 [PMID: 35889923] (IHC, Mouse)	IHC	Mouse
W Chen, B Li, F Jia, J Li, H Huang, C Ni, W Xia High PANX1 Expression Leads to Neutrophil Recruitment and the Formation of a High Adenosine Immunosuppressive Tumor Microenvironment in Basal-like Breast Cancer Cancers, 2022-07-11;14(14):. 2022-07-11 [PMID: 35884429] (IHC, Human)	IHC	Human
N Caporarell, J Lee, TX Pham, DL Jones, J Guan, PA Link, JA Meridew, G Marden, T Yamashita, CA Osborne, AV Bhagwate, SK Huang, RF Nicosia, DJ Tschumperl, M Trojanowsk, G Ligresti Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis Nature Communications, 2022-07-25;13(1):4170. 2022-07-25 [PMID: 35879310] (IHC, Mouse)	IHC	Mouse
Sung PS, Yang SP, Peng YC et al. CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation Journal of biomedical science 7/11/2022 [PMID: 35820906]
NPK Le, AF do Nascime, D Schneberge, CC Quach, X Zhang, GK Aulakh, W Dawicki, L Liu, JR Gordon, B Singh Deficiency of leukocyte-specific protein 1 (LSP1) alleviates asthmatic inflammation in a mouse model Respiratory Research, 2022-06-22;23(1):165. 2022-06-22 [PMID: 35733161] (IHC, Mouse)	IHC	Mouse
D Ye, J Yao, W Du, C Chen, Y Yang, K Yan, J Li, Y Xu, S Zang, Y Zhang, X Rong, R Zhang, A Xu, J Guo Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice Cellular and Molecular Gastroenterology and Hepatology, 2022-06-02;0(0):. 2022-06-02 [PMID: 35660025] (ICC, IHC, Western Blot, Mouse)	ICC, IHC, Western Blot	Mouse
C Arnholdt, K Kumaraswam, P Götz, M Kübler, M Lasch, E Deindl Depletion of gammadelta T Cells Leads to Reduced Angiogenesis and Increased Infiltration of Inflammatory M1-like Macrophages in Ischemic Muscle Tissue Cells, 2022-04-29;11(9):. 2022-04-29 [PMID: 35563796] (IHC, Mouse)	IHC	Mouse
Vijay M M. Ravindra, Frederik Denorme, Matthew D. Alexander, Robert A. Campbell, Ramesh Grandhi Endovascular mechanical thrombectomy in a child with COVID-19: Clot analysis reveals a novel pathway in the neuroinflammatory cascade resulting in large-vessel occlusion Interv Neuroradiol 4/21/2022 [PMID: 35450459]
Jiang S, Chan CN, Rovira-ClavE X et al. Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments Immunity 4/12/2022 [PMID: 35447093]
Paolo Carai, Laura Florit Florit González, Stijn Van Bruggen, Valerie Spalart, Daria De Giorgio, Nadéche Geuens et al. Neutrophil inhibition improves acute inflammation in a murine model of viral myocarditis Cardiovascular Research 1/18/2023 [PMID: 35426438]
Frederik Denorme, Irina Portier, John L. Rustad, Mark J. Cody, Claudia V. de Araujo, Chieko Hoki et al. Neutrophil extracellular traps regulate ischemic stroke brain injury Journal of Clinical Investigation 5/16/2022 [PMID: 35358095]
Anthony C. Y. Yau, Maria Ascencion Globisch, Favour Chinyere Onyeogaziri, Lei L. Conze, Ross Smith, Suvi Jauhiainen et al. Inflammation and neutrophil extracellular traps in cerebral cavernous malformation Cellular and Molecular Life Sciences 4/1/2022 [PMID: 35333979]
Kenji Namiguchi, Tomohisa Sakaue, Mikio Okazaki, Kaho Kanno, Yuhei Komoda, Fumiaki Shikata et al. Unique Angiogenesis From Cardiac Arterioles During Pericardial Adhesion Formation Frontiers in Cardiovascular Medicine 2/3/2022 [PMID: 35187100]
H Wang, DJ Tumes, TR Hercus, KH Yip, C Aloe, R Vlahos, AF Lopez, N Wilson, CM Owczarek, S Bozinovski Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models Cell Death & Disease, 2022-02-10;13(2):137. 2022-02-10 [PMID: 35145069] (IHC, Mouse)	IHC	Mouse
JM Adrover, L Carrau, J Da beta ler-Ple, Y Bram, V Chandar, S Houghton, D Redmond, JR Merrill, M Shevik, BR tenOever, SK Lyons, RE Schwartz, M Egeblad Disulfiram inhibits neutrophil extracellular trap formation protecting rodents from acute lung injury and SARS-CoV-2 infection JCI Insight, 2022-03-08;0(0):. 2022-03-08 [PMID: 35133984] (IHC, Hamster)	IHC	Hamster
C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch ADAM8 signaling drives neutrophil migration and ARDS severity JCI Insight, 2022-02-08;7(3):. 2022-02-08 [PMID: 35132956] (IHC, Mouse)	IHC	Mouse
Verena Staedtke, Tyler Gray-Bethke, Guanshu Liu, Eleni Liapi, Gregory J Riggins, Ren-Yuan Bai Neutrophil depletion enhanced the Clostridium novyi-NT therapy in mouse and rabbit tumor models Neuro-Oncology Advances 2/4/2022 [PMID: 35118381]
Yasuyuki Fujii, Nelson Monteiro, Shyam Kishor Sah, Homan Javaheri, Yasuyoshi Ueki, Zhichao Fan et al. Tlr2/4‐Mediated Hyperinflammation Promotes Cherubism‐Like Jawbone Expansion in Sh3bp2 (P416R) Knockin Mice JBMR Plus 1/1/2022 [PMID: 35079675]
Renata Finelli, Sara Darbandi, Peter Natesan Pushparaj, Ralf Henkel, Edmund Ko, Ashok Agarwal In Silico Sperm Proteome Analysis to Investigate DNA Repair Mechanisms in Varicocele Patients Front Endocrinol (Lausanne) 12/17/2021 [PMID: 34975746]
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Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition PLoS Pathog, 2016-05-25;12(5):e1005644. 2016-05-25 [PMID: 27223610] (IHC, Mouse)	IHC	Mouse
Lawler C, Milho R, May J, Stevenson P Rhadinovirus host entry by co-operative infection. PLoS Pathog, 2015-03-19;11(3):e1004761. 2015-03-19 [PMID: 25790477] (IHC, Mouse)	IHC	Mouse
Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking beta-glucans. PLoS ONE, 2015-03-18;10(3):e0119244. 2015-03-18 [PMID: 25786219] (IHC, Western Blot, Mouse)	IHC, Western Blot	Mouse
Bilin Dong, Dongsheng Li, Ruoyu Li, Sharon C.-A. Chen, Weihuang Liu, Wei Liu et al. A Chitin-Like Component on Sclerotic Cells of Fonsecaea pedrosoi Inhibits Dectin-1-Mediated Murine Th17 Development by Masking beta -Glucans PLoS ONE 12/9/2014 [PMID: 25490199]
Khailova L, Petrie B, Baird C, Dominguez Rieg J, Wischmeyer P Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis. PLoS ONE, 2014-05-15;9(5):e97861. 2014-05-15 [PMID: 24830455] (IHC, Mouse)	IHC	Mouse
Behnsen J, Jellbauer S, Wong C, Edwards R, George M, Ouyang W, Raffatellu M The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria. Immunity, 2014-02-06;40(2):262-73. 2014-02-06 [PMID: 24508234] (Western Blot, Mouse)	Western Blot	Mouse
Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunol, 2014-01-15;7(5):1079-93. 2014-01-15 [PMID: 24424522] (IHC, Mouse)	IHC	Mouse
Bianca Hemmeryckx, Marc F. Hoylaerts, Eveline Deloose, Cor E. Van Hove, Paul Fransen, Hidde Bult et al. Age-associated pro-inflammatory adaptations of the mouse thoracic aorta Thrombosis and Haemostasis 1/10/2013 [PMID: 23925372]
B. Joseph Hinnebusch, Clayton O. Jarrett, Julie A. Callison, Donald Gardner, Susan K. Buchanan, Gregory V. Plano Role of the Yersinia pestis Ail Protein in Preventing a Protective Polymorphonuclear Leukocyte Response during Bubonic Plague Infection and Immunity 12/1/2011 [PMID: 21969002]
Chad S. Weldy, Collin C. White, Hui-Wen Wilkerson, Timothy V. Larson, James A. Stewart, Sean E. Gill et al. Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice Inhalation Toxicology 4/21/2012 [PMID: 21967497]
Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein. PLoS Pathog., 2011-08-25;7(8):e1002202. 2011-08-25 [PMID: 21901097] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Gill SE, Huizar I, Bench EM Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury. Am. J. Pathol., 2009-12-11;176(1):64-73. 2009-12-11 [PMID: 20008147] (ELISA Development, Mouse)	ELISA Development	Mouse
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Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Aida Meghraoui	Imaging Mass Cytometry	Human	10/05/2020	View Summary Application Other Sample Tested FFPE Species Human Lot YBZ0319051
Enlarge	5 reviewed by: Verified Customer	Immunofluorescence - paraffin	Human	04/12/2019	View Summary Application Other Sample Tested human tonsil Species Human Lot I don't have it any more Comments Comments pH9 antigen retrieval
Enlarge	4 reviewed by: Verified Customer	IHC-P	Rabbit	01/11/2017	View Summary Application Immunohistochemistry-Paraffin Sample Tested Small intestine Species Rabbit Lot YBZ0216021 Comments Comments We have tested the antibody for use in rabbit. PFA-fixed ileum embedded in paraffin was used, sections were 7 micrometer thick. Details about antigen retrieval are available upon request and outlined in the attached image. We also performed WB analysis with these rabbit samples. Image available upon request. Before trying with rabbit, we used samples from mouse (previously tested species) to confirm that the antibody is working in our hands. Details available upon request. Please don't hesitte to contact us in case of questions. We woud like to participate in the Innovator Reward. Thanks.

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