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CMAS Antibody

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Western Blot: CMAS Antibody [NBP1-85858] -Analysis in human cell line NTERA-2.
Western Blot: CMAS Antibody [NBP1-85858] -Analysis in human cell line NTERA-2.
Immunohistochemistry-Paraffin: CMAS Antibody [NBP1-85858] -Staining of human colon shows strong nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: CMAS Antibody [NBP1-85858] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: CMAS Antibody [NBP1-85858] -Staining of human cerebral cortex shows strong nuclear positivity in neurons.
Immunohistochemistry-Paraffin: CMAS Antibody [NBP1-85858] -Staining of human liver shows strong nuclear positivity in hepatocytes.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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CMAS Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KMEVSVSDKLAVVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSGAPADACSTAQKAVGYICKCNGGRGAIREFAEHICLLMEKVNNSCQ
Predicted Species
Mouse (91%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CMAS
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
CMAS Protein (NBP1-85858PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for CMAS Antibody

  • CMP-N-acetylneuraminic acid synthase
  • CMP-N-acetylneuraminic acid synthetase
  • CMP-Neu5Ac synthetase
  • CMP-NeuNAc synthase
  • CMP-NeuNAc synthetase
  • cytidine 5'-monophosphate N-acetylneuraminic acid synthetase
  • cytidine monophosphate N-acetylneuraminic acid synthetase
  • EC 2.7.7.43
  • N-acylneuraminate cytidylyltransferase

Background

The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CMAS