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C1qR1/CD93 Antibody [Unconjugated]

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C1qR1/CD93 was detected in immersion fixed U937 human histiocytic lymphoma cell line using Goat Anti-Human C1qR1/CD93 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2379) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells.
C1qR1/CD93 was detected in immersion fixed U937 human histiocytic lymphoma cell line using Goat Anti-Human C1qR1/CD93 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2379) at 15 µg/mL for 3 hours ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready, ICC/IF
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Conjugate Size Price
Biotin
BAF2379
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF2379-SP
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C1qR1/CD93 Antibody [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human C1q R1/CD93
Ala24-Lys580
Accession # Q9NPY3
Specificity
Detects human C1q R1/CD93 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant mouse C1q R1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CD93
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Immunocytochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF2379 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C1qR1/CD93 Antibody [Unconjugated]

  • AA4 Antigen
  • C1q R1
  • C1q receptor 1
  • C1q Rp
  • C1q/MBL/SPA receptor
  • C1qR(P)
  • C1qR1
  • C1qRp
  • CD93 antigenC1qR
  • CD93 molecule
  • CD93
  • CDw93C1QR1
  • Collectin Receptor
  • Complement component 1 q subcomponent receptor 1
  • complement component 1, q subcomponent, receptor 1
  • complement component C1q receptor
  • dJ737E23.1
  • ECSM3
  • Ly68
  • Matrix-remodeling-associated protein 4
  • matrix-remodelling associated 4
  • MXRA4

Background

C1q R1, also known as CD93, C1q R, and C1q RP, is a single chain glycoprotein expressed on cells of myeloid origin, endothelial cells, and hematopoietic progenitor cells. In vitro, this molecule may mediate the enhancement of phagocytosis upon interaction with soluble defense collagens (1, 2).
  1. Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
  2. Dean, Y.D. and P. Gasque (2001) Eur. J. Immunol. 31:1370.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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C1qR1/CD93
Antibody [Unconjugate
AF2379
C1qR1/CD93 Antibody [Unconjugated]
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC/IF

Publications for C1qR1/CD93 Antibody (AF2379)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: ELISA (detection), ELISA Development, ELISA Development (Detection), ICC, IHC-Fr.


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ELISA (detection)
(1)
ELISA Development
(1)
ELISA Development (Detection)
(1)
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(1)
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(1)
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Human
(4)
Mouse
(1)
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Showing Publications 1 - 5 of 5.
Publications using AF2379 Applications Species
M Lee, HS Park, MY Choi, HZ Kim, SJ Moon, JY Ha, A Choi, YW Park, JS Park, EC Shin, CW Ahn, S Kang Significance of Soluble CD93 in Type 2 Diabetes as a Biomarker for Diabetic Nephropathy: Integrated Results from Human and Rodent Studies J Clin Med, 2020-05-08;9(5):. 2020-05-08 [PMID: 32397261] (ELISA (detection), Mouse) ELISA (detection) Mouse
JWD Blackburn, DHC Lau, EY Liu, J Ellins, AM Vrieze, EN Pawlak, JD Dikeakos, B Heit Soluble CD93 is an apoptotic cell opsonin recognized by ?x ?2 Eur. J. Immunol., 2019-02-07;0(0):. 2019-02-07 [PMID: 30656676] (ICC, Human) ICC Human
Lili Bao Elevated expression of CD93 promotes angiogenesis and tumor growth in nasopharyngeal carcinoma Biochem Biophys Res Commun, 2016-05-30;0(0):. 2016-05-30 [PMID: 27255994] (IHC-Fr, Human) IHC-Fr Human
Youn J, Yu H, Jeon J, Lee H, Jang Y, Park Y, Park Y, Shin E, Ha J Soluble CD93 levels in patients with acute myocardial infarction and its implication on clinical outcome. PLoS ONE, 2014-05-06;9(5):e96538. 2014-05-06 [PMID: 24801400] (ELISA Development (Detection), Human) ELISA Development (Detection) Human
Malarstig A, Silveira A, Wagsater D, Ohrvik J, Backlund A, Samnegard A, Khademi M, Hellenius ML, Leander K, Olsson T, Uhlen M, de Faire U, Eriksson P, Hamsten A Plasma CD93 concentration is a potential novel biomarker for coronary artery disease. J. Intern. Med., 2011-03-21;270(0):229-36. 2011-03-21 [PMID: 21332844] (ELISA Development, Human) ELISA Development Human

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Bioinformatics

Gene Symbol CD93
Uniprot