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BMPR-IA/ALK-3 Antibody

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Western Blot: BMPR-IA/ALK-3 Antibody [NBP2-15601] - A. 40 ug 293T whole cell lysate/extract. B. 40 ug HepG2 whole cell lysate/extract. C. 15 ug whole cell lysate/extract of human BMPR1A-transfected 293T cells.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Ch, RM, ShSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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BMPR-IA/ALK-3 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human BMPR-IA/ALK-3. The exact sequence is proprietary.
Localization
Membrane
Predicted Species
Mouse (99%), Rat (98%), Porcine (100%), Bovine (98%), Rhesus Macaque (100%), Chicken (95%), Canine (99%), Sheep (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BMPR1A
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (86%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for BMPR-IA/ALK-3 Antibody

  • ACVRLK310q23del
  • ALK-3
  • ALK3EC 2.7.11.30
  • BMP type-1A receptor
  • BMPR1A
  • BMPR-1A
  • BMPRIA
  • BMPR-IA
  • bone morphogenetic protein receptor type-1A
  • bone morphogenetic protein receptor, type IA
  • CD292 antigen
  • CD292
  • EC 2.7.11
  • Serine/threonine-protein kinase receptor R5
  • SKR5
  • type II-like kinase 3

Background

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BMPR1A
Uniprot