BMPR-IA/ALK-3 Products

Description

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Bioinformatics

Entrez	657 Human
Uniprot	AAH28383 Human BMRA_HUMAN Human CAA80257 Human NP_004320 Human NP_004320.2 Human P36894 Human
Product By Gene ID	657
Alternate Names	ACVRLK310q23del ALK-3 ALK3EC 2.7.11.30 BMP type-1A receptor BMPR-1A bone morphogenetic protein receptor type-1A bone morphogenetic protein receptor, type IA CD292 antigen CD292 EC 2.7.11 Serine/threonine-protein kinase receptor R5 SKR5 type II-like kinase 3

Research Areas for BMPR-IA/ALK-3

Find related products by research area and learn more about each of the different research areas below.

Mesenchymal Stem Cell Markers
Protein Kinase
Stem Cell Markers