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CCL26/Eotaxin-3 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA(Det)
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
AF346
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF346
Carrier Free
AF346
Carrier Free
AF346-SP
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CCL26/Eotaxin-3 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human CCL26/Eotaxin-3 (R&D Systems, Catalog # 346-E3)
Thr24-Leu94
Accession # Q9Y258
Specificity
Detects human CCL26/Eotaxin-3 in ELISAs and Western blots. In sandwich immunoassays, less than 0.5% cross-reactivity with recombinant human (rh) Eotaxin, rhEotaxin‑2, recombinant mouse (rm) Eotaxin, and rmEotaxin‑2 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CCL26
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
  • Western Blot 0.1 ug/mL
Application Notes
ELISA Capture: Human CCL26/Eotaxin-3 Antibody (Catalog # MAB653)
ELISA Detection: Human CCL26/Eotaxin-3 Biotinylated Antibody (Catalog # BAF346)
Standard: Recombinant Human CCL26/Eotaxin-3 (Catalog # 653-E3)
Readout System
Publications
Read Publications using
BAF346 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCL26/Eotaxin-3 Antibody [Biotin]

  • CC chemokine IMAC
  • C-C motif chemokine 26
  • CCL26
  • chemokine (C-C motif) ligand 26
  • chemokine N1
  • Eotaxin3
  • Eotaxin-3
  • IMAC
  • Macrophage inflammatory protein 4-alpha
  • MGC126714
  • MIP-4a
  • MIP-4alpha
  • SCYA26
  • SCYA26MIP-4-alpha
  • small inducible cytokine A26
  • small inducible cytokine subfamily A (Cys-Cys), member 26
  • Small-inducible cytokine A26
  • TSC-1Thymic stroma chemokine-1

Background

Eotaxin-3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3/CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin-3/CCL26 expression can also be detected in various tissues. The expression of Eotaxin-3/CCL26 in vascular endothelial cells has been shown to be up-regulated by IL-13 and IL-4. Eotaxin-3/CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. Eotaxin-3/CCL26 induces calcium flux in eosinophils as well as in CCR3-transfected cells. Eotaxin-3/CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands.

  1. Gou, R.F. et al. (1999) Genomics 58:313.
  2. Kitamura, M. et al. (1999) J. Biol. Chem. 274:27975.
  3. Shinkai, A. et al. (1999) J. Immunol. 163:1602.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CCL26/Eotaxin-3
Antibody [Biotin]
BAF346
CCL26/Eotaxin-3 Antibody [Biotin]
Species: Hu
Applications: WB, ELISA(Det)

Publications for CCL26/Eotaxin-3 Antibody (BAF346)(2)

We have publications tested in 2 confirmed species: Human, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 2 applications: ELISA Development, IHC.


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(1)
IHC
(1)
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(1)
Primate - Macaca mulatta (Rhesus Macaque)
(1)
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CCL26
Uniprot