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beta-III Tubulin Antibody (TuJ-1) [NL637] - Neuron-Specific

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Product Details

Summary
Reactivity All-MultiSpecies Glossary
Applications ICC/IF
Clone
TuJ-1
Clonality
Monoclonal
Host
Mouse
Conjugate
NL637

beta-III Tubulin Antibody (TuJ-1) [NL637] - Neuron-Specific Summary

Specificity
Detects neuron-specific beta -III Tubulin in Western blots.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
TUBB3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry
Publications
Read Publications using
NL1195V in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for beta-III Tubulin Antibody (TuJ-1) [NL637] - Neuron-Specific

  • Beta3-tubulin
  • beta-4
  • betaIII Tubulin
  • beta-III Tubulin
  • beta-Tubulin III
  • Class III beta-tubulin
  • TUBB3
  • TUBB4 CFEOM3A
  • Tubulin Beta 3
  • tubulin beta-3 chain
  • Tubulin beta-4 chain
  • Tubulin beta-4
  • Tubulin beta-III
  • tubulin, beta 3
  • TUJ1 antigen
  • TUJ-1 antigen

Background

beta -III Tubulin, also known as tubulin beta -4, is regarded as a neuron-specific marker. The expression of beta -III Tubulin has been suggested to be one of the earliest markers to signal commitment in primitive neuroepithelium.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for beta-III Tubulin Antibody (NL1195V)(11)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 3 applications: Flow Cytometry, ICC, IHC.


Filter By Application
Flow Cytometry
(1)
ICC
(3)
IHC
(4)
All Applications
Filter By Species
Human
(2)
Mouse
(4)
Rat
(1)
All Species
Showing Publications 1 - 10 of 11. Show All 11 Publications.
Publications using NL1195V Applications Species
Leonardo D’Aiuto, Jill K. Caldwell, Callen T. Wallace, Tristan R. Grams, Maribeth A. Wesesky, Joel A. Wood et al. The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids Cells 2022-11-09 [PMID: 36428968]
MAS de Toledo, X Fu, F Kluge, K Götz, S Schmitz, P Wanek, HM Schüler, K Pannen, N Chatain, S Koschmiede, TH Brümmendor, M Zenke CRISPR/Cas9-engineered human ES cells harboring heterozygous and homozygous c-KIT knockout Stem Cell Research, 2022-03-01;60(0):102732. 2022-03-01 [PMID: 35279545] (ICC, Human) ICC Human
Ping Shi, Lan B. Hoang-Minh, Jia Tian, Alice Cheng, Reemsha Basrai, Neil Kalaria et al. HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells Cancers (Basel) 2021-04-01 [PMID: 33915983]
Eric E. Abrahamson, Wenxiao Zheng, Vaishali Muralidaran, Milos D. Ikonomovic, David C. Bloom, Vishwajit L. Nimgaonkar et al. Modeling A beta 42 Accumulation in Response to Herpes Simplex Virus 1 Infection: Two Dimensional or Three Dimensional? Journal of Virology 2021-02-10 [PMID: 33268524]
A Jamali, K Hu, VG Sendra, T Blanco, MJ Lopez, G Ortiz, Y Qazi, L Zheng, A Turhan, DL Harris, P Hamrah Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis Cell Rep, 2020-09-01;32(9):108099. 2020-09-01 [PMID: 32877681] (ICC, IHC, Mouse) ICC, IHC Mouse
DJ Rashid, R Bradley, AM Bailleul, K Surya, HN Woodward, P Wu, YB Wu, DB Menke, SG Minchey, B Parrott, SL Bock, C Merzdorf, E Narotzky, N Burke, JR Horner, SC Chapman Distal spinal nerve development and divergence of avian groups Sci Rep, 2020-04-14;10(1):6303. 2020-04-14 [PMID: 32286419] (ICC, Human) ICC Human
K Sousounis, DM Bryant, J Martinez F, SS Eddy, SL Tsai, GC Gundberg, J Han, K Courtemanc, M Levin, JL Whited Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration Elife, 2020-03-06;9(0):. 2020-03-06 [PMID: 32142407] (IHC, Mouse) IHC Mouse
D'Aiuto L, Bloom DC, Naciri JN et al. Modeling HSV-1 infections in human CNS neuronal cells using two-dimensional and three- dimensional cultures derived from induced pluripotent stem cells J. Virol. 2019-02-20 [PMID: 30787148]
S Tighe, HR Moein, L Chua, A Cheng, P Hamrah, SC Tseng Topical Cryopreserved Amniotic Membrane and Umbilical Cord Eye Drops Promote Re-Epithelialization in a Murine Corneal Abrasion Model Invest. Ophthalmol. Vis. Sci, 2017-03-01;58(3):1586-1593. 2017-03-01 [PMID: 28288269] (IHC, Mouse) IHC Mouse
Byun Y, Kang B, Yoo Y, Joo C Poly(ADP-Ribose) Polymerase Inhibition Improves Corneal Epithelial Innervation and Wound Healing in Diabetic Rats. Invest Ophthalmol Vis Sci, 2015-02-24;56(3):1948-55. 2015-02-24 [PMID: 25711635] (IHC, Rat) IHC Rat
Show All 11 Publications.

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Secondary Antibodies

 

Isotype Controls

Additional beta-III Tubulin Products

Blogs on beta-III Tubulin.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents
Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...  Read full blog post.

Beta Tubulin III and neurogenesis
Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr...  Read full blog post.

Beta III tubulin
The Beta III tubulin protein is abundantly present in both the central and peripheral nervous systems (CNS and PNS), where it is predominantly expressed during fetal and postnatal development. In cerebellar and sympathoadrenal neurogenesis, Beta III d...  Read full blog post.

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Bioinformatics

Gene Symbol TUBB3