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beta-Defensin 3 Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, Rt, Po, CaSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

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beta-Defensin 3 Antibody [Biotin] Summary

Immunogen
A synthetic peptide made to an internal portion of Defensin beta 3 (between amino acids 10-60) [UniProt P81534]
Predicted Species
Porcine (90%), Canine (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DEFB103B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human and rat reactivity reported in (PMID: 21369366).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for beta-Defensin 3 Antibody [Biotin]

  • BD14
  • BD3
  • BD-3
  • beta-defensin 103
  • betaDefensin 3
  • beta-Defensin 3
  • DEFB103
  • DEFB103A
  • DEFB103B
  • DEFB3
  • DEFB-3
  • DEFB3DEFB103A
  • Defensin, beta 103
  • defensin, beta 103B
  • Defensin-like protein
  • HBD-3
  • HBD3HBP3

Background

Defensin beta 3 is a novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and clones from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomyosin-resistant Entoerococcus faecium. Keratinocytes and airway epithelial cells are cellular sources of hBD-3. Tumor necrosis factor alpha and contact with bacteria were found to induce hBD-3 mRNA expression. hBD-3, therefore, might be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung, such as cystic fibrosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for beta-Defensin 3 Antibody (NB200-117B) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for beta-Defensin 3 Antibody (NB200-117B)

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Blogs on beta-Defensin 3.

Beta-defensin-3: I may be small but I'm powerful!
Beta-defensin 3 is a novel, non-hemolytic antimicrobial cationic peptide originally isolated from human lesional psoriatic scales and keratinocyte clones. It is a very small (2-6 kD) yet potent salt-insensitive broad spectrum antimicrobial that ta...  Read full blog post.

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Bioinformatics

Gene Symbol DEFB103B