Species: Hu, Rt, Po, Ca
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Goat Polyclonal
Species: Hu, Po
Applications: WB
Host: Rabbit Polyclonal
Species: Mu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Mu
Applications: PAGE, Bioactivity
Species: Rt
Applications: PAGE, Bioactivity
Species: Hu
Applications: Bioactivity
Description
Defensin beta 3 is a novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and clones from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomyosin-resistant Entoerococcus faecium. Keratinocytes and airway epithelial cells are cellular sources of hBD-3. Tumor necrosis factor alpha and contact with bacteria were found to induce hBD-3 mRNA expression. hBD-3, therefore, might be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung, such as cystic fibrosis.
Bioinformatics
| Entrez |
Human
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
55894 |
| Alternate Names |
- BD3
- BD-3
- beta-defensin 103
- Beta-defensin 3
- DEFB103
- DEFB-3
- DEFB3DEFB103A
- Defensin, beta 103
- defensin, beta 103B
- Defensin-like protein
- hBD-3
- HBD3HBP3
|
Research Areas for beta-Defensin 3
Find related products by research area and learn more about each of the different research areas below.
Immunology
