beta-Defensin 3 Antibody Summary
Immunogen |
Immunized with recombinant Human beta-Defensin 3 (Uniprot#: P81534; Gly23-Lys67 (Uniprot#: P81534) |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
DEFB103B |
Purity |
Antigen and protein A Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
0.01M PBS, pH7.4, 50% glycerol |
Preservative |
0.05% Proclin 300 |
Concentration |
0.5 mg/ml |
Purity |
Antigen and protein A Affinity-purified |
Alternate Names for beta-Defensin 3 Antibody
Background
Defensin beta 3 is a novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and clones from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomyosin-resistant Entoerococcus faecium. Keratinocytes and airway epithelial cells are cellular sources of hBD-3. Tumor necrosis factor alpha and contact with bacteria were found to induce hBD-3 mRNA expression. hBD-3, therefore, might be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung, such as cystic fibrosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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