Western Blot: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-76864] - Human spleen tissue lysate with Cathelicidin antibody at 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-76864] - in Human Spleen cells.
Immunohistochemistry-Paraffin: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-76864] - IHC analysis of a formalin fixed paraffin embedded tissue section of human lymph node using 5 ug/ml dilution of CAMP antibody ...read more
Antibody was raised against a 17 amino acid synthetic peptide from an internal portion of the human Cathelicidin protein. The immunogen is located within amino acids 50 - 100 of Cathelicidin.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CAMP
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified
Alternate Names for CAMP/LL37/FALL39/Cathelicidin Antibody - BSA Free
18 kDa cationic antimicrobial protein
CAMP
CAMP/LL37
CAP18
CAP18CRAMP
cathelicidin antimicrobial peptide
CRAMP
FALL39
FALL-39
FALL39CAP-18
hCAP-18
LL37
Background
One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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