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ARHGEF6 Antibody [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

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ARHGEF6 Antibody [DyLight 350] Summary

Immunogen
The immunogen for this product maps to a region between residue 50 and 100 of human Rac/Cdc42 guanine nucleotide exchange factor 6 using the numbering given in entry NP_004831.1 (GeneID 9459).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARHGEF6
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ARHGEF6 Antibody [DyLight 350]

  • alphaPIX
  • Alpha-Pix
  • COOL-2
  • COOL2alpha
  • KIAA0006Cool2
  • mental retardation, X-linked 46
  • MRX46
  • PAK-interacting exchange factor alpha
  • PIXA
  • Rac/Cdc42 guanine exchange factor (GEF) 6
  • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Rac/Cdc42 guanine nucleotide exchange factor 6
  • rho guanine nucleotide exchange factor 6

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ARHGEF6