YY1 Antibody

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: B/N, IP, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP1-46218	Applications	Species
Zhang J, Jing L, Tan S et al. Inhibition of miR-1193 leads to synthetic lethality in glioblastoma multiforme cells deficient of DNA-PKcs Cell Death Dis 2020-07-30 [PMID: 32732911] (B/N)	B/N
Fawal MA, Jungas T, Kischel A et al. Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation Cell Rep 2018-06-05 [PMID: 29874574] (WB)	WB
Soares RJ, Cagnin S, Chemello F et al. Involvement of miRNAs in the Regulation of Muscle Wasting during Catabolic Conditions. J. Biol. Chem. 2014-06-02 [PMID: 24891504] (WB, Mouse) Details: NBP1-46218 used for WB on muscle lysate of Mice (Figure 5D) - Denervation was performed on adult, 2 month old, CD1 mice and muscles were lysed in: 50 mM Tris, pH 7.5, 150 mM NaCl, 5 mM MgCl2, 10% glycerol, 2% SDS, 1% Trirton X-100, 1mM DTT, Phosphatase inhibitor cocktail 2 and Phosphatase inhibitor cocktail 3 and Complete EDTA-free protease inhibitor mixture. Muscle lysates loaded/separated on 4-7.5% precast gels were processed for WB of YY1 and Ago2 proteins.	WB	Mouse
Holdt LM, Hoffmann S, Sass K et al. Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks. PLoS Genet 2013-07-01 [PMID: 23861667] (IP, Human)	IP	Human

Array NBP1-46218

• YY1 Antibodies
• YY1 ELISA Kits
• YY1 Lysate
• YY1 Proteins