Name: TNF RI/TNFRSF1A Antibody (16805) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB625
Price: 499 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, B/N, ELISA(Cap)
Clone	16805
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Formulation	Size	Price
Carrier Free MAB625-SP

Carrier Free MAB625-500

Immunogen	E. coli-derived recombinant human TNF RI/TNFRSF1A Extracellular domain
Specificity	Detects human TNF RI/TNFRSF1A in ELISAs and Western blots. In sandwich immunoassays, no significant cross-reactivity or interference with recombinant human (rh) TGF-alpha , hTGF-beta 1, porcine (p) TGF-beta 1, rhTGF-beta 1, pTGF-beta 1.2, pTGF-beta 2, recombinant chicken TGF-beta 3, rhTGF-beta 3, recombinant amphibian TGF-beta 5, rhTNF-beta , or rhTNF RII is observed.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	TNFRSF1A
Purity Statement	Protein A or G purified from ascites
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

TNF RI/TNFRSF1A Antibody (16805) [Unconjugated]

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Publications for TNF RI/TNFRSF1A Antibody (MAB625)(27)

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Bioinformatics

Publications using MAB625	Applications	Species
Ben-Khemis, M;Liu, D;Pintard, C;Song, Z;Hurtado-Nedelec, M;Marie, JC;El-Benna, J;Dang, PM; TNF? counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes Redox biology 2023-09-20 [PMID: 37757542] (Neutralization, Human)	Neutralization	Human
Menevse, AN;Ammer, LM;Vollmann-Zwerenz, A;Kupczyk, M;Lorenz, J;Weidner, L;Hussein, A;Sax, J;M�hlbauer, J;Heuschneider, N;Rohrmus, C;Mai, LS;Jachnik, B;Stamova, S;Volpin, V;Durst, FC;Sorrentino, A;Xydia, M;Milenkovic, VM;Bader, S;Braun, FK;Wetzel, C;Albert, NL;Tonn, JC;Bartenstein, P;Proescholdt, M;Schmidt, NO;Linker, RA;Riemenschneider, MJ;Beckhove, P;Hau, P; TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma Acta neuropathologica communications 2023-05-08 [PMID: 37158962] (Neutralization, Human)	Neutralization	Human
T Baram, N Oren, N Erlichman, T Meshel, A Ben-Baruch Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFalpha Receptors in Human Triple-Negative Breast Cancer Cancers, 2022-07-19;14(14):. 2022-07-19 [PMID: 35884574] (ELISA Capture, Human)	ELISA Capture	Human
TC Rao, RR Beggs, KE Ankenbauer, J Hwang, VP Ma, K Salaita, SL Bellis, AL Mattheyses ST6Gal-I-mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion The Journal of Biological Chemistry, 2022-02-12;0(0):101726. 2022-02-12 [PMID: 35157848] (Neutralization, Human)	Neutralization	Human
W Zhu, Q Qiu, H Luo, F Zhang, J Wu, X Zhu, M Liang High Glucose Exacerbates TNF-&alpha-Induced Proliferative Inhibition in Human Periodontal Ligament Stem Cells through Upregulation and Activation of TNF Receptor 1 Stem Cells Int, 2020-02-05;2020(0):4910767. 2020-02-05 [PMID: 32089705] (Neutralization, Human)	Neutralization	Human
Rasheed Ahmad, Shihab Kochumon, Betty Chandy, Steve Shenouda, Merin Koshy, Amal Hasan et al. TNF-alpha Drives the CCL4 Expression in Human Monocytic Cells: Involvement of the SAPK/JNK and NF-kappa B Signaling Pathways Cellular Physiology and Biochemistry 2019-04-10 [PMID: 30964608]
L Bin, X Li, B Richers, JE Streib, JW Hu, P Taylor, DYM Leung ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum J. Allergy Clin. Immunol., 2018-01-31;0(0):. 2018-01-31 [PMID: 29371118] (Neutralizing, Human)	Neutralizing	Human
CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes Sci Rep, 2016-09-27;6(0):34310. 2016-09-27 [PMID: 27670158] (Human)		Human
Steeland S, Puimege L, Vandenbroucke R, Van Hauwermeiren F, Haustraete J, Devoogdt N, Hulpiau P, Leroux-Roels G, Laukens D, Meuleman P, De Vos M, Libert C Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1. J Biol Chem, 2014-12-23;290(7):4022-37. 2014-12-23 [PMID: 25538244] (ELISA Development (Capture), Human)	ELISA Development (Capture)	Human
Christopher Loosbroock, Christopher Loosbroock Inhibiting TNF-α signaling does not attenuate induction of endotoxin tolerance Journal of Inflammation Research 2014-12-16 [PMID: 25506235]
Mayu Ueda, Takuo Fujisawa, Mitsuaki Ono, Emilio Satoshi Hara, Hai Thanh Pham, Ryu Nakajima et al. A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells Stem Cell Research & Therapy 2014-03-01 [PMID: 24580841]
Denoyer A, Godefroy D, Celerier I, Frugier J, Riancho L, Baudouin F, Rostene W, Baudouin C CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation. Mucosal Immunol, 2012-06-13;5(0):702. 2012-06-13 [PMID: 22692452] (Neutralization, Human)	Neutralization	Human
Zhao X, Qureshi F, Eastman PS, Manning WC, Alexander C, Robinson WH, Hesterberg LK Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. J. Immunol. Methods, 2012-02-17;378(1):72-80. 2012-02-17 [PMID: 22366959] (ELISA Development, Human)	ELISA Development	Human
Julie A. Bastarache, Sara C. Sebag, Brandon S. Grove, Lorraine B. Ware Interferon-gamma and tumor necrosis factor-alpha act synergistically to up-regulate tissue factor in alveolar epithelial cells Experimental Lung Research 2013-04-02 [PMID: 21913843]
Emily Turner-Brannen, Ka-Yee Grace Choi, Ryan Arsenault, Hani El-Gabalawy, Scott Napper, Neeloffer Mookherjee Inflammatory Cytokines IL-32 and IL-17 Have Common Signaling Intermediates despite Differential Dependence on TNF-Receptor 1 The Journal of Immunology 2011-06-15 [PMID: 21602493]
Krausgruber T, Saliba D, Ryzhakov G IRF5 is required for late-phase TNF secretion by human dendritic cells. Blood, 2010-03-17;115(22):4421-30. 2010-03-17 [PMID: 20237317] (Neutralization, Human)	Neutralization	Human
Hu H, Kwun J, Aizenstein BD, Knechtle SJ Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation, 2009-06-27;87(12):1814-20. 2009-06-27 [PMID: 19543058] (Antibody Array Development, Human)	Antibody Array Development	Human
Emsley HC, Smith CJ, Gavin CM Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production. BMC Neurol, 2007-02-28;7(0):5. 2007-02-28 [PMID: 17328808] (ELISA Development, Human)	ELISA Development	Human
Lee SY, Cherla RP, Tesh VL Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1. Infect. Immun., 2006-12-28;75(3):1291-302. 2006-12-28 [PMID: 17194804] (Functional Assay, Human)	Functional Assay	Human
Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. Arthritis Rheum., 2006-05-01;54(5):1451-62. 2006-05-01 [PMID: 16649193] (Neutralization, Human)	Neutralization	Human
Mozaffarian D, Rimm EB, King IB, Lawler RL, McDonald GB, Levy WC trans fatty acids and systemic inflammation in heart failure. Am. J. Clin. Nutr., 2004-12-01;80(6):1521-5. 2004-12-01 [PMID: 15585763] (ELISA Development, Human)	ELISA Development	Human
Ricci-Vitiani L, Pedini F, Mollinari C, Condorelli G, Bonci D, Bez A, Colombo A, Parati E, Peschle C, De Maria R Absence of caspase 8 and high expression of PED protect primitive neural cells from cell death. J. Exp. Med., 2004-11-15;200(10):1257-66. 2004-11-15 [PMID: 15545353] (Flow Cytometry, Human)	Flow Cytometry	Human
Chopin V, Slomianny C, Hondermarck H, Le Bourhis X Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1). Exp. Cell Res., 2004-08-15;298(2):560-73. 2004-08-15 [PMID: 15265702] (Western Blot, Human)	Western Blot	Human
Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (Array Development, Human)	Array Development	Human
Gee K, Lim W, Ma W, Nandan D, Diaz-Mitoma F, Kozlowski M, Kumar A Differential regulation of CD44 expression by lipopolysaccharide (LPS) and TNF-alpha in human monocytic cells: distinct involvement of c-Jun N-terminal kinase in LPS-induced CD44 expression. J. Immunol., 2002-11-15;169(10):5660-72. 2002-11-15 [PMID: 12421945] (Neutralization, Human)	Neutralization	Human
Jyonouchi H, Sun S, Itokazu N Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. Neuropsychobiology, 2002-01-01;46(2):76-84. 2002-01-01 [PMID: 12378124] (ELISA Development, Human)	ELISA Development	Human
Bharucha AE, 2019, Jorgensen R, Lichtman SN, LaRusso NF, Lindor KD A pilot study of pentoxifylline for the treatment of primary sclerosing cholangitis. 2000-09-01;95(9):2338-42. 2000-09-01 [PMID: 11007239] (ELISA Development, Human)	ELISA Development	Human
Show All 27 Publications. Collapse Publications.