Independent Antibodies: Western Blot: TIF1 alpha Antibody [NB100-2597] - Detection of Human TIF1 alpha/TRIM24 on HeLa whole cell lysate (5, 15, and 50 microgram) and 293T cell lysate (50 microgram) using ...read more
The immunogen recognized by this antibody maps to a region between residue 1,000 and the C-terminus (residue 1050) of human Transcriptional Intermediary Factor 1 Alpha (NP_056989.2).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRIM24
Purity
Immunogen affinity purified
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Use in Immunohistochemistry-paraffin and Immunohistochemistry-Frozen reported in scientific literature (PMID: 23006314). Use in ICC/IF was reported in scientific literature (PMID: 23006314).
Theoretical MW
117 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NB100-2597 in the following applications:
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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