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TIAM2 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: TIAM2 Antibody [NBP1-80713] - Staining of human cell line A-431 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: TIAM2 Antibody [NBP1-80713] - Staining of human cerebral cortex shows strong positivity in neuropil.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TIAM2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: IKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TIAM2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
TIAM2 Protein (NBP1-80713PEP)
Publications
Read Publications using
NBP1-80713 in the following applications:

Reactivity Notes

Reactivity reported in scientific literature (PMID: 25646088)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TIAM2 Antibody

  • FLJ41865
  • KIAA2016
  • SIF and TIAM1-like exchange factor
  • STEFTIAM-2
  • T-cell lymphoma invasion and metastasis 2
  • T-lymphoma invasion and metastasis-inducing protein 2

Background

TIAM2 encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TIAM2 Antibody (NBP1-80713)(3)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol TIAM2
Entrez