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TGF-beta RII Antibody (176510) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
176510
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB2411-SP
Carrier Free
MAB2411-500
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TGF-beta RII Antibody (176510) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human TGF‑ beta  RII isoform 2
Thr23-Asp184
Accession # NP_001020018
Specificity
Detects human TGF-beta RII and TGF-beta RIIb in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human TGF-beta RIII, recombinant mouse (rm) TGF-beta RII, or rmTGF-beta RI.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TGFBR2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Publications
Read Publication using
MAB2411 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TGF-beta RII Antibody (176510) [Unconjugated]

  • AAT3
  • EC 2.7.11
  • EC 2.7.11.30
  • FAA3
  • HNPCC6
  • LDS1B
  • LDS2B
  • MFS2
  • RIIC
  • TAAD2
  • tbetaR-II
  • TGF-beta receptor type II
  • TGF-beta receptor type IIB
  • TGF-beta receptor type-2
  • TGF-beta RII
  • TGF-beta type II receptor
  • TGFbetaRII
  • TGFbeta-RII
  • TGFBR2
  • TGF-bRII
  • TGFR-2
  • transforming growth factor beta receptor type IIC
  • transforming growth factor, beta receptor II (70/80kDa) isoform 1
  • transforming growth factor, beta receptor II (70/80kDa) isoform 2
  • transforming growth factor, beta receptor II (70/80kDa)
  • transforming growth factor, beta receptor II (70-80kD)
  • Transforming growth factor-beta receptor type II

Background

TGF-beta RII is a membrane-bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TGF-beta RII
Antibody (176510) [Un ...
MAB2411
TGF-beta RII Antibody (176510) [Unconjugated]
Species: Hu
Applications: WB

Publications for TGF-beta RII Antibody (MAB2411)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Immunoprecipitation.


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Bioinformatics

Gene Symbol TGFBR2
Uniprot