Saurat, N;Minotti, AP;Rahman, MT;Sikder, T;Zhang, C;Cornacchia, D;Jungverdorben, J;Ciceri, G;Betel, D;Studer, L; Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration Cell stem cell 2024-06-21 [PMID: 38917806] (Bioassay, Human) |
Bioassay |
Human |
Kojima, R;Paslawski, W;Lyu, G;Arenas, E;Zhang, X;Svenningsson, P; Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations International journal of molecular sciences 2024-01-04 [PMID: 38203854] (Bioassay, Human) |
Bioassay |
Human |
Ely, EV;Kapinski, AT;Paradi, SG;Tang, R;Guilak, F;Collins, KH; Designer Fat Cells: Adipogenic Differentiation of CRISPR-Cas9 Genome-Engineered Induced Pluripotent Stem Cells bioRxiv : the preprint server for biology 2023-10-26 [PMID: 37961399] (Bioassay, Mouse) |
Bioassay |
Mouse |
Aouimeur, I;Sagnial, T;Coulomb, L;Maurin, C;Thomas, J;Forestier, P;Ninotta, S;Perrache, C;Forest, F;Gain, P;Thuret, G;He, Z; Investigating the Role of TGF-? Signaling Pathways in Human Corneal Endothelial Cell Primary Culture Cells 2023-06-14 [PMID: 37371094] (ICC, Human) |
ICC |
Human |
Z You, L Wang, H He, Z Wu, X Zhang, S Xue, P Xu, Y Hong, M Xiong, W Wei, Y Chen Mapping of clonal lineages across developmental stages in human neural differentiation Cell Stem Cell, 2023-03-17;0(0):. 2023-03-17 [PMID: 36933556] (Bioassay, Human) |
Bioassay |
Human |
Z You, L Wang, H He, Z Wu, X Zhang, S Xue, P Xu, Y Hong, M Xiong, W Wei, Y Chen Mapping of clonal lineages across developmental stages in human neural differentiation Cell Stem Cell, 2023;0(0):. 2023 [PMID: 36933556] (Bioassay, Human) |
Bioassay |
Human |
AR Dicks, GI Maksaev, Z Harissa, A Savadipour, R Tang, N Steward, W Liedtke, CG Nichols, CL Wu, F Guilak Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes Elife, 2023-02-22;12(0):. 2023-02-22 [PMID: 36810131] (Bioassay, Human) |
Bioassay |
Human |
K Santerre, S Cortez Ghi, S Proulx TGF-beta-Mediated Modulation of Cell-Cell Interactions in Postconfluent Maturing Corneal Endothelial Cells Investigative Ophthalmology & Visual Science, 2022-10-03;63(11):3. 2022-10-03 [PMID: 36194422] (Bioassay, Human) |
Bioassay |
Human |
I Hanson, KE Pitman, U Altanerova, ? Altaner, E Malinen, NFJ Edin Low-Dose-Rate Radiation-Induced Secretion of TGF-beta3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding International Journal of Molecular Sciences, 2022-07-24;23(15):. 2022-07-24 [PMID: 35897723] (Bioassay, Human) |
Bioassay |
Human |
L Wang, G Lin, Z Zuo, Y Li, SK Byeon, A Pandey, HJ Bellen Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia Oncogene, 2022-07-13;8(28):eabn3326. 2022-07-13 [PMID: 35857503] (Bioassay, Drosophila melanogaster) |
Bioassay |
Drosophila melanogaster |
J Kim, J Jeon, B Song, N Lee, S Ko, Y Cha, P Leblanc, H Seo, KS Kim Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells Nature Protocols, 2022-02-09;0(0):. 2022-02-09 [PMID: 35140411] (Bioassay, Human) |
Bioassay |
Human |
M Melzer, S Schubert, SF Müller, J Geyer, A Hagen, S Niebert, J Burk Rho/ROCK Inhibition Promotes TGF-beta3-Induced Tenogenic Differentiation in Mesenchymal Stromal Cells Stem Cells International, 2021-10-08;2021(0):8284690. 2021-10-08 [PMID: 34659420] (Bioassay, Human) |
Bioassay |
Human |
V Padmanabha, H Liu, G Ciceri, J Jungverdor, G Frishman, J Tchieu, GY Cederquist, I Rothenaign, K Schorpp, L Klepper, RM Walsh, TW Kim, D Cornacchia, A Ruepp, J Mayer, K Hadian, D Frishman, L Studer, M Vincendeau Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3 Cell Stem Cell, 2021-05-04;0(0):. 2021-05-04 [PMID: 33951478] (Bioassay, Human) |
Bioassay |
Human |
Y Ikeda-Iwab, Y Taniyama, N Katsuragi, F Sanada, N Koibuchi, K Shibata, K Shimazu, H Rakugi, R Morishita Periostin Short Fragment with Exon 17 via Aberrant Alternative Splicing Is Required for Breast Cancer Growth and Metastasis Cells, 2021-04-14;10(4):. 2021-04-14 [PMID: 33919736] (Bioassay, Human) |
Bioassay |
Human |
HN Kim, JY Shin, DY Kim, JE Lee, PH Lee Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models Journal of tissue engineering, 2021-03-30;12(0):2041731421100. 2021-03-30 [PMID: 33854750] (Differentiation, Differentiation, Mouse) |
Differentiation, Differentiation |
Mouse |
N Franceschi, B Verbruggen, MA Tryfonidou, AB Kruisselbr, H Baelde, KE de Visser, K Szuhai, AM Cleton-Jan, JVMG Bovée Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics Cancers, 2021-03-05;13(5):. 2021-03-05 [PMID: 33807947] (Bioassay, Canine, Mouse) |
Bioassay |
Canine, Mouse |
Y Tao, SC Vermilyea, M Zammit, J Lu, M Olsen, JM Metzger, L Yao, Y Chen, S Phillips, JE Holden, V Bondarenko, WF Block, TE Barnhart, N Schultz-Da, K Brunner, H Simmons, BT Christian, ME Emborg, SC Zhang Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys Nature Medicine, 2021-03-01;0(0):. 2021-03-01 [PMID: 33649496] (Bioassay, Primate - Rhesus macaque) |
Bioassay |
Primate - Rhesus macaque |
KJG Kenswil, P Pisterzi, G Sánchez-Du, C van Dijk, A Lolli, C Knuth, B Vanchin, AC Jaramillo, RM Hoogenboez, MA Sanders, J Feyen, T Cupedo, IG Costa, R Li, EMJ Bindels, K Lodder, B Blom, PK Bos, MJ Goumans, P Ten Dijke, E Farrell, G Krenning, MHGP Raaijmaker Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation Cell Stem Cell, 2021-02-08;0(0):. 2021-02-08 [PMID: 33561425] (Bioassay, Human) |
Bioassay |
Human |
TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel, ND Socci, SJ Choi, S Zabierowsk, BN Dubose, EJ Hill, EV Mosharov, S Irion, MJ Tomishima, V Tabar, L Studer Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use Cell Stem Cell, 2021-02-04;28(2):343-355.e5. 2021-02-04 [PMID: 33545081] (Bioassay, Human) |
Bioassay |
Human |
S Nürnberger, C Schneider, C Keibl, B Schädl, P Heimel, X Monforte, AH Teuschl, M Nalbach, PJ Thurner, J Grillari, H Redl, S Wolbank Repopulation of decellularised articular cartilage by laser-based matrix engraving EBioMedicine, 2021-01-19;0(0):103196. 2021-01-19 [PMID: 33483297] (Bioassay, Human) |
Bioassay |
Human |
T Otsuka, PY Mengsteab, CT Laurencin Control of mesenchymal cell fate via application of FGF-8b in vitro Stem Cell Research, 2021-01-07;51(0):102155. 2021-01-07 [PMID: 33445073] (Bioassay, Rat) |
Bioassay |
Rat |
CL Wu, A Dicks, N Steward, R Tang, DB Katz, YR Choi, F Guilak Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis Nature Communications, 2021-01-13;12(1):362. 2021-01-13 [PMID: 33441552] (Bioassay, Human) |
Bioassay |
Human |
L Chen, K Shi, W Qiu, L Aagaard, M Kassem Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation Stem Cells International, 2020-08-19;2020(0):8857344. 2020-08-19 [PMID: 32922451] (Bioassay, Human) |
Bioassay |
Human |
YH Kim, GY Park, N Rabinovitc, S Tarafder, CH Lee Effect of local anesthetics on viability and differentiation of various adult stem/progenitor cells Stem Cell Res Ther, 2020-09-07;11(1):385. 2020-09-07 [PMID: 32894184] (Cell Culture, Human) |
Cell Culture |
Human |
JW Kim, X Yin, A Jhaldiyal, MR Khan, I Martin, Z Xie, T Perez-Rose, M Kumar, L Abalde-Atr, J Xu, L Chen, SM Eacker, DJ Surmeier, NT Ingolia, TM Dawson, VL Dawson Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis Cell Stem Cell, 2020-08-25;27(4):633-645.e7. 2020-08-25 [PMID: 32846140] (Bioassay, Human) |
Bioassay |
Human |
SK Meurer, O Tezcan, T Lammers, R Weiskirche Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells Cell. Signal., 2020-08-03;74(0):109731. 2020-08-03 [PMID: 32758668] (Bioassay, Human) |
Bioassay |
Human |
L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020-06-19;27(1):125-136.e7. 2020-06-19 [PMID: 32579880] (Bioassay, Human) |
Bioassay |
Human |
L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020;27(1):125-136.e7. 2020 [PMID: 32579880] (Bioassay, Human) |
Bioassay |
Human |
L Bundgaard, A Stensballe, KJ Elbæk, LC Berg Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells to assess the effect of chondrogenic differentiation on response to interleukin-1&beta treatment Stem Cell Res Ther, 2020-05-20;11(1):187. 2020-05-20 [PMID: 32434555] (Cell Culture, Horse) |
Cell Culture |
Horse |
I Rajpar, JG Barrett Multi-differentiation potential is necessary for optimal tenogenesis of tendon stem cells Stem Cell Res Ther, 2020-04-09;11(1):152. 2020-04-09 [PMID: 32272975] (Bioassay, Horse) |
Bioassay |
Horse |
A Dicks, CL Wu, N Steward, SS Adkar, CA Gersbach, F Guilak Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter Stem Cell Res Ther, 2020-02-18;11(1):66. 2020-02-18 [PMID: 32070421] (Cell Culture, Human) |
Cell Culture |
Human |
Y Wu, K Chen, G Xing, L Li, B Ma, Z Hu, L Duan, X Liu Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition Sci Adv, 2019-11-27;5(11):eaax7525. 2019-11-27 [PMID: 31807705] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
S Mahajani, A Raina, C Fokken, S Kügler, M Bähr Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors Cell Death Dis, 2019-11-27;10(12):898. 2019-11-27 [PMID: 31776327] (Cell Culture, Human) |
Cell Culture |
Human |
D Leitner, M Ramamoorth, M Dejosez, TP Zwaka Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation Stem Cell Res, 2019-10-24;41(0):101617. 2019-10-24 [PMID: 31731178] (Cell Culture, In vitro, Human, Mouse) |
Cell Culture, In vitro |
Human, Mouse |
J Lovecchio, P Gargiulo, JL Vargas Lun, E Giordano, ÓE Sigurjónss A standalone bioreactor system to deliver compressive load under perfusion flow to hBMSC-seeded 3D chitosan-graphene templates Sci Rep, 2019-11-14;9(1):16854. 2019-11-14 [PMID: 31728040] (Cell Culture, Human) |
Cell Culture |
Human |
O Daniels, J Frisch, JK Venkatesan, A Rey-Rico, G Schmitt, M Cucchiarin Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment J Clin Med, 2019-10-07;8(10):. 2019-10-07 [PMID: 31591319] (Bioassay, Human) |
Bioassay |
Human |
HC O'Neill, HK Lim, P Periasamy, L Kumarappan, JKH Tan, TJ O'Neill Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis PLoS ONE, 2019-10-04;14(10):e0223416. 2019-10-04 [PMID: 31584977] (Bioassay, Mouse) |
Bioassay |
Mouse |
M Riessland, B Kolisnyk, TW Kim, J Cheng, J Ni, JA Pearson, EJ Park, K Dam, D Acehan, LS Ramos-Espi, W Wang, J Zhang, JW Shim, G Ciceri, L Brichta, L Studer, P Greengard Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons Cell Stem Cell, 2019-09-19;25(4):514-530.e8. 2019-09-19 [PMID: 31543366] (Bioassay, Human) |
Bioassay |
Human |
Y Kawakami, WS Hambright, K Takayama, X Mu, A Lu, JH Cummins, T Matsumoto, T Yurube, R Kuroda, M Kurosaka, FH Fu, PD Robbins, LJ Niedernhof, J Huard Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice Mol Ther Methods Clin Dev, 2019-05-30;14(0):64-76. 2019-05-30 [PMID: 31312666] (Bioassay, Mouse) |
Bioassay |
Mouse |
A Shojaee, A Parham, F Ejeian, MH Nasr Esfah Equine adipose mesenchymal stem cells (eq-ASCs) appear to have higher potential for migration and musculoskeletal differentiation Res. Vet. Sci., 2019-07-03;125(0):235-243. 2019-07-03 [PMID: 31310927] (Bioassay, Equine, Human) |
Bioassay |
Equine, Human |
X Wu, M Ma, P Wang, Z Xie, S Wang, H Su, W Deng, P Feng, C Su, J Yang, J Li, S Tang, Y Wu, H Shen ?2-HS Glycoprotein in Plasma Extracellular Vesicles Inhibits the Osteogenic Differentiation of Human Mesenchymal Stromal Cells In Vitro Stem Cells Int, 2019-02-07;2019(0):7246479. 2019-02-07 [PMID: 30881463] (Bioassay, Human) |
Bioassay |
Human |
A Wehrle, TM Witkos, S Unger, J Schneider, JA Follit, J Hermann, T Welting, V Fano, M Hietala, N Vatanavich, K Schoner, J Spranger, M Schmidts, B Zabel, GJ Pazour, A Bloch-Zupa, G Nishimura, A Superti-Fu, M Lowe, E Lausch Hypomorphic mutations of TRIP11 cause odontochondrodysplasia JCI Insight, 2019-02-07;4(3):. 2019-02-07 [PMID: 30728324] (Bioassay, Human) |
Bioassay |
Human |
J Lee, SJ Kwon, JH Kim, H Jang, NK Lee, JW Hwang, JH Kim, JW Chang, DL Na Cerebrospinal fluid from Alzheimer's disease patients as an optimal formulation for therapeutic application of mesenchymal stem cells in Alzheimer's disease Sci Rep, 2019-01-24;9(1):564. 2019-01-24 [PMID: 30679696] (Bioassay, Human) |
Bioassay |
Human |
TS Fu, YH Wei, PY Cheng, IM Chu, WC Chen A Novel Biodegradable and Thermosensitive Poly(Ester-Amide) Hydrogel for Cartilage Tissue Engineering Biomed Res Int, 2018-12-19;2018(0):2710892. 2018-12-19 [PMID: 30662902] (Bioassay, Rabbit) |
Bioassay |
Rabbit |
M Kim, DR Steinberg, JA Burdick, RL Mauck Extracellular vesicles mediate improved functional outcomes in engineered cartilage produced from MSC/chondrocyte cocultures Proc. Natl. Acad. Sci. U.S.A., 2019-01-15;116(5):1569-1578. 2019-01-15 [PMID: 30647113] (Bioassay, Bovine) |
Bioassay |
Bovine |
JS Park, M Kim, NJ Song, JH Kim, D Seo, JH Lee, SM Jung, JY Lee, J Lee, YS Lee, KW Park, SH Park A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells Stem Cells, 2018-12-07;0(0):. 2018-12-07 [PMID: 30444564] (Bioassay, Mouse) |
Bioassay |
Mouse |
KA de Lima, PB Donate, J Talbot, M Davoli-Fer, RS Peres, TM Cunha, JC Alves-Filh, FQ Cunha TGF?1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism Cell Death Dis, 2018-11-13;9(11):1130. 2018-11-13 [PMID: 30425241] (Bioassay, Mouse) |
Bioassay |
Mouse |
SS Adkar, CL Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, F Guilak Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing Stem Cells, 2018-10-31;0(0):. 2018-10-31 [PMID: 30378731] (Bioassay, Human) |
Bioassay |
Human |
J Riegger, HG Palm, RE Brenner The functional role of chondrogenic stem/progenitor cells: novel evidence for immunomodulatory properties and regenerative potential after cartilage injury Eur Cell Mater, 2018-09-14;36(0):110-127. 2018-09-14 [PMID: 30215457] (Bioassay, Human) |
Bioassay |
Human |
H Lin, E Hay, A Latourte, T Funck-Bren, W Bouaziz, HK Ea, AM Khatib, P Richette, M Cohen-Sola Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGF?-dependent manner and limits osteoarthritis in mice Sci Rep, 2018-07-11;8(1):10488. 2018-07-11 [PMID: 29992982] (Bioassay, Mouse) |
Bioassay |
Mouse |
G Collo, L Cavalleri, M Zoli, U Maskos, E Ratti, E Merlo Pich Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons Front Pharmacol, 2018-06-01;9(0):572. 2018-06-01 [PMID: 29910731] (Bioassay, Human) |
Bioassay |
Human |
MM Adil, DV Schaffer hPSC-derived Midbrain Dopaminergic Neurons Generated in a Scalable 3-D Biomaterial Curr Protoc Stem Cell Biol, 2018-02-28;44(0):2D.21.1-2D.21. 2018-02-28 [PMID: 29512105] (Bioassay, Human) |
Bioassay |
Human |
H Jing, B Gao, M Gao, H Yin, X Mo, X Zhang, K Luo, B Feng, W Fu, J Wang, W Zhang, M Yin, Z Zhu, X He, J Zheng Restoring tracheal defects in a rabbit model with tissue engineered patches based on TGF-?3-encapsulating electrospun poly(l-lactic acid-co-?-caprolactone)/collagen scaffolds Artif Cells Nanomed Biotechnol, 2018-02-15;0(0):1-11. 2018-02-15 [PMID: 29448837] (Bioassay, Rabbit) |
Bioassay |
Rabbit |
M Desancé, R Contentin, L Bertoni, T Gomez-Ledu, T Branly, S Jacquet, JM Betsch, A Batho, F Legendre, F Audigié, P Galéra, M Demoor Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Int J Mol Sci, 2018-02-10;19(2):. 2018-02-10 [PMID: 29439436] (Bioassay, Equine) |
Bioassay |
Equine |
J Nishida, K Miyazono, S Ehata Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-?-dependent and -independent mechanisms Oncogene, 2018-02-02;0(0):. 2018-02-02 [PMID: 29391598] (Bioassay, Human) |
Bioassay |
Human |
T Branly, R Contentin, M Desancé, T Jacquel, L Bertoni, S Jacquet, F Mallein-Ge, JM Denoix, F Audigié, M Demoor, P Galéra Improvement of the Chondrocyte-Specific Phenotype upon Equine Bone Marrow Mesenchymal Stem Cell Differentiation: Influence of Culture Time, Transforming Growth Factors and Type I Collagen siRNAs on the Differentiation Index Int J Mol Sci, 2018-02-01;19(2):. 2018-02-01 [PMID: 29389887] (Bioassay, Equine) |
Bioassay |
Equine |
DM Lord, JJ Bird, DM Honey, A Best, A Park, RR Wei, H Qiu Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF?1 antibody MAbs, 2018-02-01;0(0):0. 2018-02-01 [PMID: 29333938] (Human) |
|
Human |
U Mayer, A Benditz, S Grässel miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment Sci Rep, 2017-10-16;7(1):13297. 2017-10-16 [PMID: 29038440] (Bioassay, Human) |
Bioassay |
Human |
D Parate, A Franco-Obr, J Fröhlich, C Beyer, AA Abbas, T Kamarul, JHP Hui, Z Yang Enhancement of mesenchymal stem cell chondrogenesis with short-term low intensity pulsed electromagnetic fields Sci Rep, 2017-08-25;7(1):9421. 2017-08-25 [PMID: 28842627] (Bioassay, Human) |
Bioassay |
Human |
K Hino, K Horigome, M Nishio, S Komura, S Nagata, C Zhao, Y Jin, K Kawakami, Y Yamada, A Ohta, J Toguchida, M Ikeya Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva J. Clin. Invest., 2017-07-31;0(0):. 2017-07-31 [PMID: 28758906] (Bioassay, Human) |
Bioassay |
Human |
S Stich, A Loch, SJ Park, T Häupl, J Ringe, M Sittinger Characterization of single cell derived cultures of periosteal progenitor cells to ensure the cell quality for clinical application PLoS ONE, 2017-05-31;12(5):e0178560. 2017-05-31 [PMID: 28562645] (Bioassay, Human) |
Bioassay |
Human |
M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential PLoS ONE, 2017-05-18;12(5):e0177771. 2017-05-18 [PMID: 28542363] (Bioassay, Human) |
Bioassay |
Human |
HH Wu, OK Lee Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells Stem Cell Res Ther, 2017-05-23;8(1):117. 2017-05-23 [PMID: 28535778] (Bioassay, Mouse) |
Bioassay |
Mouse |
SI Pao, KH Chien, HT Lin, MC Tai, JT Chen, CM Liang Effect of microgravity on the mesenchymal stem cell characteristics of limbal fibroblasts J Chin Med Assoc, 2017-05-18;0(0):. 2017-05-18 [PMID: 28529022] (Bioassay, Mouse) |
Bioassay |
Mouse |
JM Brunger, A Zutshi, VP Willard, CA Gersbach, F Guilak Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs Stem Cell Reports, 2017-04-27;0(0):. 2017-04-27 [PMID: 28457885] (Bioassay, Mouse) |
Bioassay |
Mouse |
M Arase, Y Tamura, N Kawasaki, K Isogaya, R Nakaki, A Mizutani, S Tsutsumi, H Aburatani, K Miyazono, D Koinuma Dynamics of chromatin accessibility during TGF-?-induced EMT of Ras-transformed mammary gland epithelial cells Sci Rep, 2017-04-26;7(1):1166. 2017-04-26 [PMID: 28446749] (Bioassay, Mouse) |
Bioassay |
Mouse |
L Mei, B Shen, P Ling, S Liu, J Xue, F Liu, H Shao, J Chen, A Ma, X Liu Culture-expanded allogenic adipose tissue-derived stem cells attenuate cartilage degeneration in an experimental rat osteoarthritis model PLoS ONE, 2017-04-18;12(4):e0176107. 2017-04-18 [PMID: 28419155] (Bioassay, Rat) |
Bioassay |
Rat |
J Rodriguez, AS Pratta, N Abbassi, H Fabre, F Rodriguez, C Debard, J Adobati, F Boucher, F Mallein-Ge, C Auxenfans, O Damour, A Mojallal Evaluation of Three Devices for the Isolation of the Stromal Vascular Fraction from Adipose Tissue and for ASC Culture: A Comparative Study Stem Cells Int, 2017-02-22;2017(0):9289213. 2017-02-22 [PMID: 28321259] (Bioassay, Human) |
Bioassay |
Human |
MD Truong, BH Choi, YJ Kim, MS Kim, BH Min Granulocyte macrophage-colony stimulating factor (GM-CSF) significantly enhances articular cartilage repair potential by microfracture Osteoarthr. Cartil, 2017-03-08;0(0):. 2017-03-08 [PMID: 28284999] (Bioassay, Rabbit) |
Bioassay |
Rabbit |
SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE Mnch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres Neurotoxic reactive astrocytes are induced by activated microglia Nature, 2017-01-18;541(7638):481-487. 2017-01-18 [PMID: 28099414] (Bioassay, Human) |
Bioassay |
Human |
Elias S, Schmidt A, Kannan V, Andersson J, Tegner J TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner. Front Immunol, 2016-12-23;7(0):603. 2016-12-23 [PMID: 28066414] (Bioassay, Human) |
Bioassay |
Human |
Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation BMC Biotechnol, 2016-12-12;16(1):89. 2016-12-12 [PMID: 27955656] (Bioassay, Human) |
Bioassay |
Human |
Mélanie Gadelorge Clinical-scale expansion of Adipose derived Stromal Cells starting from Stromal Vascular Fraction in a single-use bioreactor: Proof of concept for autologous applications J Tissue Eng Regen Med, 2017-05-12;0(0):. 2017-05-12 [PMID: 27943660] (Bioassay, Human) |
Bioassay |
Human |
Sarah Hemming EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity, and accelerates remodeling FASEB J, 2016-12-01;0(0):. 2016-12-01 [PMID: 27934660] (Bioassay, Mouse) |
Bioassay |
Mouse |
Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells PLoS ONE, 2016-12-01;11(12):e0167442. 2016-12-01 [PMID: 27907211] (Bioassay, Canine) |
Bioassay |
Canine |
Weiguo Zou Bromodomain and Extra-terminal Proteins (BET) Inhibitors Suppress Chondrocyte Differentiation and Restrain Bone Growth J. Biol. Chem., 2016-11-07;0(0):. 2016-11-07 [PMID: 27821592] (Bioassay, Mouse) |
Bioassay |
Mouse |
Aberrant Transforming Growth Factor-? Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia Stem Cells Transl Med, 2016-01-01;0(0):. 2016-01-01 [PMID: 27604218] (Bioassay, Mouse) |
Bioassay |
Mouse |
Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow-derived counterparts J Tissue Eng, 2016-08-16;7(0):2041731416661. 2016-08-16 [PMID: 27579159] (Bioassay, Rat) |
Bioassay |
Rat |
Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing Proc Natl Acad Sci USA, 2016-07-18;0(0):. 2016-07-18 [PMID: 27432980] (Bioassay, Human) |
Bioassay |
Human |
IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice J Immunol, 2016-05-13;0(0):. 2016-05-13 [PMID: 27183574] (Bioassay, Human) |
Bioassay |
Human |
Lepage S, Nagy K, Sung H, Kandel R, Nagy A, Koch T Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells. Stem Cells Dev, 2015-11-05;25(1):80-9. 2015-11-05 [PMID: 26414480] (Bioassay, Equine) |
Bioassay |
Equine |
Russell K, Gibson T, Chong A, Co C, Koch T Canine Platelet Lysate Is Inferior to Fetal Bovine Serum for the Isolation and Propagation of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells. PLoS ONE, 2015-09-09;10(9):e0136621. 2015-09-09 [PMID: 26353112] (Bioassay, Canine) |
Bioassay |
Canine |
Lee C, Rodeo S, Fortier L, Lu C, Erisken C, Mao J Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep. Sci Transl Med, 2014-12-10;6(266):266ra171. 2014-12-10 [PMID: 25504882] (Bioassay, Ovine) |
Bioassay |
Ovine |
Liu G, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla R, Goebl A, Aizawa E, Kim N, Kim J, Dubova I, Li Y, Ren R, Benner C, del Sol A, Bueren J, Trujillo J, Surralles J, Cappelli E, Dufour C, Esteban C, Izpisua Belmonte J Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun, 2014-07-07;5(0):4330. 2014-07-07 [PMID: 24999918] (Bioassay, Human) |
Bioassay |
Human |
Jakobsen R, Ostrup E, Zhang X, Mikkelsen T, Brinchmann J Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE, 2014-05-09;9(5):e96615. 2014-05-09 [PMID: 24816923] (Bioassay, Human) |
Bioassay |
Human |
Chen P, Liu K, Hsu P, Wei C, Bai C, Ho L, Sytwu H, Yen B Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2. J Leukoc Biol, 2014-04-08;96(2):295-303. 2014-04-08 [PMID: 24714552] (Bioassay, Human) |
Bioassay |
Human |
Karamichos D, Hutcheon A, Rich C, Trinkaus-Randall V, Asara J, Zieske J In vitro model suggests oxidative stress involved in keratoconus disease. Sci Rep, 2014-04-09;4(0):4608. 2014-04-09 [PMID: 24714342] (Bioassay, Human) |
Bioassay |
Human |
Lee S, Yoon D, Paik S, Lee K, Jang Y, Lee J microRNA-495 inhibits chondrogenic differentiation in human mesenchymal stem cells by targeting Sox9. Stem Cells Dev, 2014-04-28;23(15):1798-808. 2014-04-28 [PMID: 24654627] (Bioassay, Human) |
Bioassay |
Human |
Zhang H, Yin Y, Wang G, Liu Z, Liu L, Sun F Interleukin-6 disrupts blood-testis barrier through inhibiting protein degradation or activating phosphorylated ERK in Sertoli cells. Sci Rep, 2014-03-03;4(0):4260. 2014-03-03 [PMID: 24584780] (Bioassay, Rat) |
Bioassay |
Rat |
Brunger J, Huynh N, Guenther C, Perez-Pinera P, Moutos F, Sanchez-Adams J, Gersbach C, Guilak F Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci U S A, 2014-02-18;111(9):E798-806. 2014-02-18 [PMID: 24550481] (Bioassay) |
Bioassay |
|
Karamichos D, Funderburgh M, Hutcheon A, Zieske J, Du Y, Wu J, Funderburgh J A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells. PLoS ONE, 2014-01-21;9(1):e86260. 2014-01-21 [PMID: 24465995] (Bioassay, Human) |
Bioassay |
Human |
Belzile , Jean-Phi, Stark , Thomas J, Yeo , Gene W, Spector , Deborah Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. J Virol, 2014-01-22;88(8):4021-39. 2014-01-22 [PMID: 24453373] (Bioassay, Human) |
Bioassay |
Human |
Boyette , Lisa B, Creasey , Olivia A, Guzik , Lynda, Lozito , Thomas, Tuan , Rocky S Human bone marrow-derived mesenchymal stem cells display enhanced clonogenicity but impaired differentiation with hypoxic preconditioning. Stem Cells Transl Med, 2014-01-16;3(2):241-54. 2014-01-16 [PMID: 24436440] (Bioassay, Human) |
Bioassay |
Human |
Wada , Naohisa, Maeda , Hidefumi, Hasegawa , Daigaku, Gronthos , Stan, Bartold , Peter Ma, Menicanin , Danijela, Fujii , Shinsuke, Yoshida , Shinichi, Tomokiyo , Atsushi, Monnouchi , Satoshi, Akamine , Akifumi Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells. Stem Cells Dev, 2014-02-10;23(18):2225-36. 2014-02-10 [PMID: 24380401] (Bioassay, Human) |
Bioassay |
Human |
Espagnolle N, Guilloton F, Deschaseaux F, Gadelorge M, Sensebe L, Bourin P CD146 expression on mesenchymal stem cells is associated with their vascular smooth muscle commitment. J Cell Mol Med, 2013-11-04;18(1):104-14. 2013-11-04 [PMID: 24188055] (Bioassay, Human) |
Bioassay |
Human |
Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, Hollander A Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 2013-12-04;23(5):541-54. 2013-12-04 [PMID: 24172175] (Bioassay, Human) |
Bioassay |
Human |
Guerit D, Philipot D, Chuchana P, Toupet K, Brondello J, Mathieu M, Jorgensen C, Noel D Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells. PLoS ONE, 2013-04-23;8(4):e62582. 2013-04-23 [PMID: 23626837] (Bioassay, Human) |
Bioassay |
Human |
Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O MicroRNA-based promotion of human neuronal differentiation and subtype specification. PLoS ONE, 2013-03-18;8(3):e59011. 2013-03-18 [PMID: 23527072] (Bioassay, Human) |
Bioassay |
Human |
Lund , Troy C, Kobs , Amanda J, Kramer , Ashley, Nyquist , Mick, Kuroki , Marcos T, Osborn , John, Lidke , Diane S, Low-Nam , Shalini, Blazar , Bruce R, Tolar , Jakub Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression. PLoS ONE, 2013-03-08;8(3):e58945. 2013-03-08 [PMID: 23520545] (Bioassay, Human) |
Bioassay |
Human |
Li O, Tormin A, Sundberg B, Hyllner J, Le Blanc K, Scheding S Human embryonic stem cell-derived mesenchymal stroma cells (hES-MSCs) engraft in vivo and support hematopoiesis without suppressing immune function: implications for off-the shelf ES-MSC therapies. PLoS ONE, 2013-01-29;8(1):e55319. 2013-01-29 [PMID: 23383153] (Cell Culture, Human) |
Cell Culture |
Human |
Qian H, Badaloni A, Chiara F, Stjernberg J, Polisetti N, Nihlberg K, Consalez G, Sigvardsson M Molecular characterization of prospectively isolated multipotent mesenchymal progenitors provides new insight into the cellular identity of mesenchymal stem cells in mouse bone marrow. Mol Cell Biol, 2012-11-26;33(4):661-77. 2012-11-26 [PMID: 23184664] (Bioassay, Mouse) |
Bioassay |
Mouse |
Le M, Naridze R, Morrison J, Biggs L, Rhea L, Schutte B, Kaartinen V, Dunnwald M Transforming growth factor Beta 3 is required for excisional wound repair in vivo. PLoS ONE, 2012-10-26;7(10):e48040. 2012-10-26 [PMID: 23110169] (In Vivo, Mouse) |
In Vivo |
Mouse |
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 2012-07-26;487(7408):505-9. 2012-07-26 [PMID: 22763448] (Bioassay, Human) |
Bioassay |
Human |
Kawabata K, Ehata S, Komuro A, Takeuchi K, Miyazono K TGF-beta-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20. Oncogene, 2012-06-04;32(16):2096-106. 2012-06-04 [PMID: 22665052] (Bioassay, Human) |
Bioassay |
Human |
Qian H, Le Blanc K, Sigvardsson M Primary Mesenchymal Stem and Progenitor Cells from Bone Marrow Lack Expression of CD44 Protein. J. Biol. Chem., 2012-05-31;287(31):25795-807. 2012-05-31 [PMID: 22654106] (Bioassay, Human) |
Bioassay |
Human |
Asumda FZ, Chase PB Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol., 2011-10-12;12(0):44. 2011-10-12 [PMID: 21992089] (Bioassay, Rat) |
Bioassay |
Rat |
Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 2011-07-07;286(34):30034-46. 2011-07-07 [PMID: 21737454] (Surface Plasmon Resonance, Human, Mouse) |
Surface Plasmon Resonance |
Human, Mouse |
Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol. Biol. Cell, 2011-03-16;22(10):1686-98. 2011-03-16 [PMID: 21411626] (Bioassay, Canine) |
Bioassay |
Canine |
Kawaguchi J, Nichols J, Gierl MS, Faial T, Smith A Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development, 2010-03-01;137(5):693-704. 2010-03-01 [PMID: 20147374] (Bioassay, Mouse) |
Bioassay |
Mouse |
Moransard M, Sawitzky M, Fontana A, Suter T Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia, 2010-04-01;58(5):559-71. 2010-04-01 [PMID: 19941340] (Bioassay, Mouse) |
Bioassay |
Mouse |
English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells. Clin. Exp. Immunol., 2009-02-03;156(1):149-60. 2009-02-03 [PMID: 19210524] (Differentiation, Differentiation, Human) |
Differentiation, Differentiation |
Human |
Moioli EK, Clark PA, Sumner DR, Mao JJ Autologous stem cell regeneration in craniosynostosis. Bone, 2007-10-17;42(2):332-40. 2007-10-17 [PMID: 18023269] (In Vivo, Rat) |
In Vivo |
Rat |
Fujikawa T, Matsumura S, Yamada H, Inoue K, Fushiki T Transforming growth factor-beta in the brain enhances fat oxidation via noradrenergic neurons in the ventromedial and paraventricular hypothalamic nucleus. Brain Res., 2007-08-09;1173(0):92-101. 2007-08-09 [PMID: 17765878] (In Vivo, Rat) |
In Vivo |
Rat |
Neurohr C, Nishimura SL, Sheppard D Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am. J. Respir. Cell Mol. Biol., 2006-03-30;35(2):252-9. 2006-03-30 [PMID: 16574941] (Bioassay, Human) |
Bioassay |
Human |
Nagineni CN, Kutty V, Detrick B, Hooks JJ Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol., 2005-04-01;203(1):35-43. 2005-04-01 [PMID: 15368539] (Bioassay, Human) |
Bioassay |
Human |
Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A., 2004-08-13;101(34):12543-8. 2004-08-13 [PMID: 15310843] (Bioassay, Human, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Human, Primate - Macaca mulatta (Rhesus Macaque) |
Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22. 2004-01-12 [PMID: 14722222] (Bioassay, Human) |
Bioassay |
Human |
Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. Int. J. Dev. Biol., 2003-02-01;47(1):15-29. 2003-02-01 [PMID: 12653248] (In Vivo, Xenopus) |
In Vivo |
Xenopus |
Schmidt A, 2019, Gopfert C, Vlodavsky I, Volker W, Buddecke E Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta. 101211, 2002-03-01;81(3):138-44. 2002-03-01 [PMID: 11998865] (Bioassay, Bovine) |
Bioassay |
Bovine |
Liu X, Kohyama T, Wang H, Zhu YK, Wen FQ, Kim HJ, Romberger DJ, Rennard SI Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am. J. Physiol. Lung Cell Mol. Physiol., 2002-05-01;282(5):L1049-56. 2002-05-01 [PMID: 11943670] (ELISA (Standard)) |
ELISA (Standard) |
|
Simpson H, 2019, Robson SC, Bulmer JN, Barber A, Lyall F Transforming growth factor beta expression in human placenta and placental bed during early pregnancy. 6897, 2002-01-01;23(1):44-58. 2002-01-01 [PMID: 11869091] (ELISA (Standard)) |
ELISA (Standard) |
|
Mozes MM, Hodics T, Kopp JB Isoform specificity of commercially-available anti-TGF-beta antibodies. J. Immunol. Methods, 1999-05-27;225(1):87-93. 1999-05-27 [PMID: 10365785] (Western Blot) |
Western Blot |
|
Show All 122 Publications.
Collapse Publications.
|