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TCAP Antibody

Images

 
Western Blot: TCAP Antibody [NBP1-85544] - Analysis in human skeletal muscle tissue.
Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544] - Staining of human heart muscle shows distinct cytoplasmic positivity.
Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544] - Staining of human heart muscle shows strong cytoplasmic positivity in cardiomyocytes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TCAP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: CEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLPEYQ
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TCAP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TCAP Protein (NBP1-85544PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TCAP Antibody

  • 19 kDa sarcomeric protein
  • CMD1NTitin cap protein
  • LGMD2G
  • limb girdle muscular dystrophy 2G (autosomal recessive)
  • T-cap
  • TELE
  • telethonin
  • titin-cap (telethonin)

Background

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol TCAP