beta Sarcoglycan Antibody

The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: B/N, IF/IHC, WB.

Showing Publications 1 - 7 of 7.

Publications using NBP1-90300	Applications	Species
Davy Vanhoutte, Tobias G. Schips, Rachel A. Minerath, Jiuzhou Huo, Naga Swathi Sree Kavuri, Vikram Prasad, Suh-Chin Lin, Michael J. Bround, Michelle A. Sargent, Christopher M. Adams, Jeffery D. Molkentin Thbs1 regulates skeletal muscle mass in a TGF beta -Smad2/3-ATF4-dependent manner Cell reports 2024-06-26 [PMID: 38678560]
Baumann CW, Lindsay A, Sidky SR et al. Contraction-Induced Loss of Plasmalemmal Electrophysiological Function Is Dependent on the Dystrophin Glycoprotein Complex Frontiers in Physiology 2021-10-26 [PMID: 34764884] (WB, B/N)	WB, B/N
Sidky SR, Ingalls CP, Lowe DA, Baumann CW. Membrane Proteins Increase with the Repeated Bout Effect Medicine & Science in Sports & Exercise 2022-01-01 [PMID: 34334717] (B/N, WB)	B/N, WB
Brody MJ, Vanhoutte D, Schips TG et al. Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy Mol. Cell. Biol. 2018-04-30 [PMID: 29712757] (Mouse)		Mouse
Pozsgai ER, Griffin DA, Heller KN et al. Systemic AAV-Mediated b-Sarcoglycan Delivery Targeting Cardiac and Skeletal Muscle Ameliorates Histological and Functional Deficits in LGMD2E Mice. Mol. Ther. 2017-03-08 [PMID: 28284983] (WB, Mouse)	WB	Mouse
Vanhoutte D, Schips TG, Kwong JQ et al. Thrombospondin expression in myofibers stabilizes muscle membranes. Elife 2016-09-26 [PMID: 27669143] (IF/IHC)	IF/IHC
Pozsgai ER, Griffin DA, Heller KN et al. b-Sarcoglycan gene transfer decreases fibrosis and restores force in LGMD2E mice. Gene Ther. 2015-08-20 [PMID: 26214262] (WB, Mouse)	WB	Mouse

Array NBP1-90300

• beta Sarcoglycan Antibodies
• beta Sarcoglycan Lysate
• beta Sarcoglycan Proteins