TAF10 Antibody

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 4 applications: IHC-P, Immunoprecipitation, WB, Western Blot.

Showing Publications 1 - 3 of 3.

Publications using NBP1-80706	Applications	Species
Xiong Y, Wang L, Xu S et al. Small molecule Z363 co-regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth Clinical and Translational Medicine 2023-01-13 [PMID: 36639831] (Immunoprecipitation, Western Blot)	Immunoprecipitation, Western Blot
Seth A, Bournat JC, Medina-Martinez O et al. Loss of WNT4 in the gubernaculum causes unilateral cryptorchidism and fertility defects Development (Cambridge, England) 2022-12-01 [PMID: 36448532] (IHC-P) Details: Dilution used 1:500	IHC-P
Choi SW, Oh H, Park SY et al. Netrin-1 attenuates hepatic steatosis via UNC5b/PPAR gamma -mediated suppression of inflammation and ER stress Life sciences 2022-12-15 [PMID: 36400204] (WB, Mouse) Details: Dilution used in WB 1:1000	WB	Mouse

Array NBP1-80706

• TAF10 Antibodies
• TAF10 Lysate
• TAF10 Proteins