Synaptophysin Antibody - BSA Free

Communication in the nervous system is dependent on the exocytosis of neurotransmitter-containing synaptic vesicles that release their contents at the synapses following membrane depolarization. Synaptophysin (SYP) is a major 38 kDa tetraspan membrane protein of small synaptic vesicles that plays an essential role in targeting synaptic vesicles to the presynaptic membrane. Synaptophysin directly interacts with the essential membrane fusion v-SNARE protein, synaptobrevin/VAMP2, and targets it to the presynaptic membrane (PMID: 14528015). Thus, synaptophysin is required for proper targeting of VAMP2 and synaptic vesicles. Synaptophysin is localized to the trans-Golgi cisternae and then accumulates to the presynaptic membrane in a microtubule dependent manner (PMID: 8227215).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 6 applications: FLOW, ICC/IF, IF/IHC, IHC-Fr, IHC-P, WB.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using NBP2-25170	Applications	Species
Huynh B Brainstem Neurotransmitter System Deterioration in Parkinson's Disease and Parkinson's Disease with Dementia Thesis 2023-01-01 (WB, Human)	WB	Human
He B, Gao R, Lv S et al. Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness Signal transduction and targeted therapy 2023-07-19 [PMID: 37463926] (ICC/IF, Human)	ICC/IF	Human
Lima BHM, Bombeiro AL, Cartarozzi LP, Oliveira ALR. The Time Course of MHC-I Expression in C57BL/6J and A/J Mice Correlates with the Degree of Retrograde Gliosis in the Spinal Cord following Sciatic Nerve Crush Cells 2022-11-22 [PMID: 36496969]
Ignarro RS, Bombeiro AL, Chiarotto GB et al. Interferon-beta induces major histocompatibility complex of class I (MHC-I) expression and a proinflammatory phenotype in cultivated human astrocytes Differentiation; research in biological diversity 2022-10-15 [PMID: 36306693] (FLOW, Rat) Details: Dilution used in Flow 1:100	FLOW	Rat
Ramasubramanian B, Griffith C, Hanson M et al. Protective Effects of Chaya against Mitochondrial and Synaptic Toxicities in the Type 2 Diabetes Mouse Model TallyHO Cells 2022-02-21 [PMID: 35203393] (WB, IF/IHC, Mouse)	WB, IF/IHC	Mouse
Cartarozzi LP, Perez M, Fernandes GG et al. Neuroprotection and gliosis attenuation by intravenous application of human mesenchymal stem cells (hMSC) following ventral root crush in mice Molecular and cellular neurosciences 2021-12-24 [PMID: 34954382] (IF/IHC)	IF/IHC
Awasthi S, Hindle A, Sawant NA Et al. RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease Cells 2021-11-10 [PMID: 34831336]
Toro CA, Hansen J, Siddiq MM et al. The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice Frontiers in Cellular Neuroscience 2021-02-18 [PMID: 33679326]
Chavez-Valdez R, Lechner C, Emerson P et al. Accumulation of PSA-NCAM marks nascent neurodegeneration in the dorsal hippocampus after neonatal hypoxic-ischemic brain injury in mice J. Cereb. Blood Flow Metab. 2020-07-23 [PMID: 32703109]
Cartarozzi LP, Perez M, Kirchhoff F, Oliveira ALR Role of MHC-I Expression on Spinal Motoneuron Survival and Glial Reactions Following Ventral Root Crush in Mice Cells 2019-05-21 [PMID: 31117227] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Bernardes D, Rodrigues de Oliveira AL Regular Exercise Modifies Histopathological Outcomes of Pharmacological Treatment in Experimental Autoimmune Encephalomyelitis Frontiers 2019-11-20 [PMID: 30524355] (IHC-P, Mouse)	IHC-P	Mouse
Show All 11 Publications. Collapse Publications.

Array NBP2-25170

• Synaptophysin Antibodies
• Synaptophysin ELISA Kits
• Synaptophysin Lysate
• Synaptophysin Proteins