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STAT3 Antibody (OTI21E7) [FITC]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI21E7
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-74378AF350
Alexa Fluor 405
NBP2-74378AF405
Alexa Fluor 488
NBP2-74378AF488
Alexa Fluor 532
NBP2-74378AF532
Alexa Fluor 594
NBP2-74378AF594
Alexa Fluor 647
NBP2-74378AF647
Alexa Fluor 700
NBP2-74378AF700
Alexa Fluor 750
NBP2-74378AF750
Biotin
NBP2-74378B
CoraFluor 1
NBP2-74378CL1
DyLight 350
NBP2-74378UV
DyLight 405
NBP2-74378V
DyLight 488
NBP2-74378G
DyLight 550
NBP2-74378R
DyLight 594
NBP2-74378DL594
DyLight 650
NBP2-74378C
DyLight 680
NBP2-74378FR
DyLight 755
NBP2-74378IR
HRP
NBP2-74378H
Janelia Fluor 525
NBP2-74378JF525
Janelia Fluor 549
NBP2-74378JF549
Janelia Fluor 585
NBP2-74378JF585
Janelia Fluor 635
NBP2-74378JF635
Janelia Fluor 646
NBP2-74378JF646
Janelia Fluor 669
NBP2-74378JF669
Unconjugated
NBP1-48014
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-48014
Azide and BSA Free
NBP2-74378
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STAT3 Antibody (OTI21E7) [FITC] Summary

Immunogen
Recombinant protein expressed in E.coli corresponding to amino acids 154-175 of human STAT3.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
STAT3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for STAT3 Antibody (OTI21E7) [FITC]

  • Acute-phase response factor
  • APRFMGC16063
  • DNA-binding protein APRF
  • FLJ20882
  • HIES
  • signal transducer and activator of transcription 3 (acute-phase responsefactor)
  • signal transducer and activator of transcription 3
  • STAT3

Background

Stat3 is a member of a group of proteins (Signal Transduction and Activators of Transcription) that act as both signal transducers for cytokines and growth factors, as well as transcription factors (1,2). Stats are activated by tyrosine phosphorylation in response to different ligands, after which they translocate to the cell nucleus (1). Stat3 is constitutively activated in a number of human tumors (3). Stat3 is activated by phosphorylation on tyrosine 705 which induces dimerization, nuclear translocation, and DNA binding While, Stat3-activated transcription seems to be regulated by serine phosphorylation at serine 727 (4)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STAT3