SOX6 Antibody

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IHC-Fr, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-85811	Applications	Species
Gunawardhana KL, Hong L, Rugira T et al. A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension The Journal of clinical investigation 2023-01-05 [PMID: 36602864] (IHC-Fr, Mouse) Details: Dilution for IHC-Fr - 1:300	IHC-Fr	Mouse
Dong P, Xiong Y, Yu J et al. Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer Oncogene 2018-05-31 [PMID: 29855617] (WB, Human)	WB	Human
Fernandes AM, Herlofsen SR, Karlsen TA et al. Similar Properties of Chondrocytes from Osteoarthritis Joints and Mesenchymal Stem Cells from Healthy Donors for Tissue Engineering of Articular Cartilage. PLoS One 2013-01-01 [PMID: 23671648]
Stadler C, Rexhepaj E, Singan VR et al. Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nat Methods 2013-04-01 [PMID: 23435261]
Herlofsen SR, Kuchler AM, Melvik JE et al. Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in self-gelling alginate discs reveals novel chondrogenic signature gene clusters. Tissue Eng Part A 2011-04-01 [PMID: 21087199]

Array NBP1-85811

• SOX6 Antibodies
• SOX6 Lysate
• SOX6 Proteins