Antibody was raised against an 18 amino acid synthetic peptide near the center of human ZIP10. The immunogen is located within amino acids 550 - 600 of ZIP10. Amino Acid Squence: AGTDDSVVSEDRLNETEL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC39A10
Purity
Peptide affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified
Alternate Names for SLC39A10 Antibody - BSA Free
DKFZp564L2123
DKFZp781L10106
FLJ90515
KIAA1265
LZT-Hs2
MGC126565
MGC138428
solute carrier family 39 (metal ion transporter), member 10
solute carrier family 39 (zinc transporter), member 10
Solute carrier family 39 member 10
zinc transporter ZIP10
ZIP10
ZIP-10
Zrt- and Irt-like protein 10
Background
ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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