Could you provide the immunogen sequence of this antibody?

Name: SLC31A1/CTR1 Antibody
Brand: Novus Biologicals
SKU: NB100-402
Price: 399 USD

Question

Accepted Answer

The immunogen sequence for this product is considered proprietary, but I can tell you it falls within amino acids 160-190 of CTR1.

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Mu, Rt, Po, Ca, Xp, ZeSpecies Glossary
Applications	WB, ICC/IF, IHC
Clonality	Polyclonal
Host	Rabbit
Conjugate	Unconjugated
Concentration	1 mg/ml

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 NB100-402AF350

Alexa Fluor 405 NB100-402AF405

Alexa Fluor 488 NB100-402AF488

Alexa Fluor 532 NB100-402AF532

Alexa Fluor 594 NB100-402AF594

Alexa Fluor 647 NB100-402AF647

Alexa Fluor 700 NB100-402AF700

Alexa Fluor 750 NB100-402AF750

Allophycocyanin NB100-402APC

Biotin NB100-402B

DyLight 350 NB100-402UV

DyLight 405 NB100-402V

DyLight 488 NB100-402G

DyLight 550 NB100-402R

DyLight 594 NB100-402DL594

DyLight 650 NB100-402C

DyLight 680 NB100-402FR

DyLight 755 NB100-402IR

FITC NB100-402F

HRP NB100-402H

Janelia Fluor 549 NB100-402JF549

Janelia Fluor 646 NB100-402JF646

PE NB100-402PE

PerCP NB100-402PCP

mFluor Violet 450 SE NB100-402MFV450

mFluor Violet 500 SE NB100-402MFV500

mFluor Violet 610 SE NB100-402MFV610

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	NB100-402AF350
Alexa Fluor 405	NB100-402AF405
Alexa Fluor 488	NB100-402AF488
Alexa Fluor 532	NB100-402AF532
Alexa Fluor 594	NB100-402AF594
Alexa Fluor 647	NB100-402AF647
Alexa Fluor 700	NB100-402AF700
Alexa Fluor 750	NB100-402AF750
Allophycocyanin	NB100-402APC
Biotin	NB100-402B
DyLight 350	NB100-402UV
DyLight 405	NB100-402V
DyLight 488	NB100-402G
DyLight 550	NB100-402R
DyLight 594	NB100-402DL594
DyLight 650	NB100-402C
DyLight 680	NB100-402FR
DyLight 755	NB100-402IR
FITC	NB100-402F
HRP	NB100-402H
Janelia Fluor 549	NB100-402JF549
Janelia Fluor 646	NB100-402JF646
PE	NB100-402PE
PerCP	NB100-402PCP
mFluor Violet 450 SE	NB100-402MFV450
mFluor Violet 500 SE	NB100-402MFV500
mFluor Violet 610 SE	NB100-402MFV610

Immunogen	A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [Uniprot: O15431]
Localization	Cell Membrane
Isotype	IgG
Clonality	Polyclonal
Host	Rabbit
Gene	SLC31A1
Purity	Immunogen affinity purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

SLC31A1/CTR1 Antibody

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Publications for SLC31A1/CTR1 Antibody (NB100-402)(33)

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Storage	Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer	PBS
Preservative	0.02% Sodium Azide
Concentration	1 mg/ml
Purity	Immunogen affinity purified

Publications using NB100-402	Applications	Species
Fantin J, Toutain J, Pérès EA et al. Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies EJNMMI research 2023-11-25 [PMID: 38006431] (IHC-Fr, Human)	IHC-Fr	Human
Zhang X, Jiang Q, Su Y et al. AMPK phosphorylates and stabilises copper transporter 1 to synergise metformin and copper chelator for breast cancer therapy British journal of cancer 2023-02-17 [PMID: 36807336]
Shin VY, Liu MX, Siu JM et al. Inhibition of EP2 receptor suppresses tumor growth and chemoresistance of gastric cancer American journal of cancer research 2022-10-15 [PMID: 36381319] (WB, Human)	WB	Human
Choi H, Oh D, Kim M et al. Copper deficiency affects the developmental competence of porcine oocytes matured in vitro Frontiers in Cell and Developmental Biology 2022-09-07 [PMID: 36158185] (ICC/IF)	ICC/IF
Saifi MA, Godugu C Copper chelation therapy inhibits renal fibrosis by modulating copper transport proteins BioFactors (Oxford, England) 2022-03-24 [PMID: 35322483]
Aloysius Dhivya M, Sulochana K, Devi S High glucose induced inflammation is inhibited by copper chelation via rescuing mitochondrial fusion protein 2 in retinal pigment epithelial cells Cellular Signalling 2022-01-01 [PMID: 34999205] (WB, Human)	WB	Human
Liu LL, Du D, Zheng W, Zhang Y Age-dependent Decline of Copper Clearance at the Blood-Cerebrospinal Fluid Barrier Neurotoxicology 2021-10-27 [PMID: 34718061] (IF/IHC, WB, Rat)	IF/IHC, WB	Rat
Guo J, Cheng J, Zheng N Et Al. Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021-07-18 [PMID: 34278744]
Schoonover KE, Kennedy WM, Roberts RC Cortical copper transporter expression in schizophrenia: interactions of risk gene dysbindin-1 Journal of neural transmission (Vienna, Austria : 1996) 2021-04-22 [PMID: 33890175] (WB, Human)	WB	Human
Tsai TL, Lai YH, Hw Chen H, Su WC Overcoming Radiation Resistance by Iron-Platinum Metal Alloy Nanoparticles in Human Copper Transport 1-Overexpressing Cancer Cells via Mitochondrial Disturbance International journal of nanomedicine 2021-03-09 [PMID: 33727814] (WB, Human)	WB	Human
Schoonover KE, Farmer CB, Morgan CJ, et al. Abnormalities in the copper transporter CTR1 in postmortem hippocampus in schizophrenia: A subregion and laminar analysis Schizophrenia research 2021-01-09 [PMID: 33434736] (IF/IHC)	IF/IHC
Schoonover KE, Roberts RC Markers of copper transport in the cingulum bundle in schizophrenia Schizophrenia research 2021-01-09 [PMID: 33434726] (WB, Human)	WB	Human
Yu Z, Mersaoui S, Guitton-Sert L et al. DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions NAR Cancer 2020-10-05 [PMID: 33015627] (WB)	WB
Aubert L, Nandagopal N, Steinhart Z et al. Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer Nat Commun 2020-07-24 [PMID: 32709883] (IHC-P)	IHC-P
Morrell A, Tripet B, Eilers B et al. Copper modulates sex-specific fructose hepatoxicity in non-alcoholic fatty liver disease (NALFD) Wistar rat models The Journal of Nutritional Biochemistry 2019-12-01 [PMID: 31986483] (WB, Rat)	WB	Rat
Yong L, Ma Y, Liang C et al. Oleandrin sensitizes human osteosarcoma cells to cisplatin by preventing degradation of the copper transporter 1 Phytother Res 2019-05-02 [PMID: 31050072] (IF/IHC, Human)	IF/IHC	Human
Ishihara K, Kawashita E, Shimizu R et al. Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome Free Radic. Biol. Med. 2019-01-18 [PMID: 30660502] (WB, Mouse)	WB	Mouse
Schoonover KE, Queern SL, Lapi SE, Roberts RC. Impaired copper transport in schizophrenia results in a copper-deficient brain state: A new side to the dysbindin story The World Journal of Biological Psychiatry 2020-01-02 [PMID: 30230404] (WB)	WB
Ahn C, Choi JS, Jeung EB. Organ-specific expression of the divalent ion channel proteins NCKX3, TRPV2, CTR1, ATP7A, IREG1 and HEPH in various canine organs Mol Med Rep 2018-06-07 [PMID: 29901089] (Canine)		Canine
Bu I, Hamacher A, Sarin N, Kassack MU. Relevance of copper transporter 1 and organic cation transporters 1-3 for oxaliplatin uptake and drug resistance in colorectal cancer cells. Metallomics. 2018-02-08 [PMID: 29417972] (Human)		Human
Schneider V, Chaib S, Spanier C et al. Transporter-Mediated Interaction Between Platinum Drugs and Sorafenib at the Cellular Level. AAPS J 2017-11-30 [PMID: 29192345] (WB)	WB
Doherty Ben, Lawlor Denise, Gillet Jean-Pierre et al. Collateral sensitivity to cisplatin in KB-8-5-11 drug-resistant cancer cells. Anticancer Res. 2014-01-01 [PMID: 24403508] (Human)		Human
Yoshida H, Teramae M, Yamauchi M et al. Association of copper transporter expression with platinum resistance in epithelial ovarian cancer Anticancer Res 2013-04-01 [PMID: 23564780]
Ip V, Liu JJ, McKeage MJ et al. Evaluation of effects of copper histidine on Ctr1-mediated accumulation of platinum and oxaliplatin-induced neurotoxicity in vitro and in vivo. Clin Exp Pharmacol Physiol 2013-04-05 [PMID: 23556474] (IF/IHC, Rat)	IF/IHC	Rat
Liu JJ, Kim Y, Yan F et al. Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons Biochem Pharmacol 2012-10-31 [PMID: 23123662] (ICC/IF, Rat)	ICC/IF	Rat
Stordal B, Hamon M, McEneaney V et al. Resistance to Paclitaxel in a Cisplatin-Resistant Ovarian Cancer Cell Line Is Mediated by P-Glycoprotein plos One 2012-01-01 [PMID: 22792399] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Pourvali K, Matak P, Latunde-Dada GOet al. Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2? FEBS Lett 2012-06-07 [PMID: 22684009] (WB, Human)	WB	Human
Chen DB, Feng L, Lin XP, Zhang W, Li FR, Liang XL, Li XH. Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice. PLoS One;7(5):e37709. 2012-01-01 [PMID: 22629446] (IF/IHC, WB, IHC-Fr, Mouse)	IF/IHC, WB, IHC-Fr	Mouse
Schoonover K, Roberts R. Isoform and protein region abnormalities of dysbindin and copper transporter proteins in postmortem schizophrenia substantia nigra. bioRxiv 2018-06-09 (WB, Human)	WB	Human
More SS, Akil O, Ianculescu AG et al. Role of the copper transporter, CTR1, in platinum-induced ototoxicity. J Neurosci;30(28):9500-9. 2010-07-14 [PMID: 20631178] (WB, IHC-Fr, Mouse)	WB, IHC-Fr	Mouse
Jandial DD et al. Enhanced delivery of cisplatin to intraperitoneal ovarian carcinomas mediated by the effects of bortezomib on the human copper transporter 1. Clin Cancer Res;15(2):553-60. 2009-01-15 [PMID: 19147760]
Peng, Fangyu et al. PET of human prostate cancer xenografts in mice with increased uptake of 64CuCl2. J Nucl Med;47(10):1649-52. 2006-10-01 [PMID: 17015901]
Holzer, AK et al. Expression of the human copper influx transporter 1 in normal and malignant human tissues. J Histochem Cytochem;54(9):1041-9. 2006-09-01 [PMID: 16709730]
Show All 33 Publications. Collapse Publications.