![Protein Array: SDHB Antibody (SDHB/2382) [NBP3-08537] - Analysis of Protein Array containing more than 19,000 full-length human proteins using SDHB Mouse Monoclonal Antibody (SDHB/2382).](http://images.novusbio.com/fullsize/SDHB-Antibody-SDHB-2382-Protein-Array-NBP3-08537-img0001.jpg "Protein Array: SDHB Antibody (SDHB/2382) [NBP3-08537] - Analysis of Protein Array containing more than 19,000 full-length human proteins using SDHB Mouse Monoclonal Antibody (SDHB/2382).")
| Reactivity | HuSpecies Glossary |
| Applications | WB, MA |
| Clone | SDHB/2382 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Format | Azide and BSA Free |
| Concentration | 1 mg/ml |
| Description | 1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07787). Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. |
| Immunogen | Recombinant fragment (around aa 165-273) of human SDHB protein (exact sequence is proprietary) (Uniprot: P21912) |
| Localization | Cytoplasmic (Mitochondria) |
| Marker | Pheochromocytoma Marker |
| Specificity | Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation. Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST. |
| Isotype | IgG2b Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | SDHB |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution for a specific application should be determined. |
| Theoretical MW | 32 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Storage | Store at -20 to -80C. Avoid freeze-thaw cycles. |
| Buffer | 10 mM PBS |
| Preservative | No Preservative |
| Concentration | 1 mg/ml |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for SDHB Antibody (NBP3-08537)Find related products by research area.
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| Gene Symbol | SDHB |
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