SDHC Antibody (3E2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 4 of 4.

Publications using H00006391-M01	Applications	Species
Trombetti S, Iaccarino N, Riccio P et al. Over-Expressed GATA-1S, the Short Isoform of the Hematopoietic Transcriptional Factor GATA-1, Inhibits Ferroptosis in K562 Myeloid Leukemia Cells by Preventing Lipid Peroxidation Antioxidants 2023-02-21 [PMID: 36978786] (WB, Human)	WB	Human
Trombetti S, Sessa R, Catapano R Et al. Exploring the Leukemogenic Potential of GATA-1S, the Shorter Isoform of GATA-1: Novel Insights into Mechanisms Hampering Respiratory Chain Complex II Activity and Limiting Oxidative Phosphorylation Efficiency Antioxidants (Basel, Switzerland) 2021-10-12 [PMID: 34679737] (WB, Human)	WB	Human
Yan B, Stantic M, Zobalova R et al. Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer. 2015-05-24 [PMID: 25967547] (WB, Human)	WB	Human
Dong L-F, Freeman R, Liu J et al. Suppression of Tumor Growth In vivo by the Mitocan {alpha}-tocopheryl Succinate Requires Respiratory Complex II. Clin Cancer Res;15(5):1593-1600. 2009-01-01 [PMID: 19223492]

Array H00006391-M01

• SDHC Antibodies
• SDHC Lysate