Western Blot: RNF34 Antibody [NBP2-56413] - Analysis in human cell line HEL.
Immunocytochemistry/ Immunofluorescence: RNF34 Antibody [NBP2-56413] - Staining of human cell line CACO-2 shows localization to nuclear bodies. Antibody staining is shown in green.
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: NIVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLKVKDL
Predicted Species
Mouse (97%), Rat (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RNF34
Purity
Affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified
Alternate Names for RNF34 Antibody
CARP1
Caspase regulator CARP1
Caspases-8 and -10-associated RING finger protein 1
E3 ubiquitin-protein ligase RNF34
EC 6.3.2
EC 6.3.2.-
FLJ21786
FYVE-RING finger protein Momo
hRFI
Human RING finger homologous to inhibitor of apoptosis protein
RFI
RIF
RIFF
ring finger protein 34CARP-1
RING finger protein RIFF
Background
The protein encoded by the RNF34 gene contains a RINF finger, a motif known to be involved in protein-protein andprotein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as amodulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alphainduced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have beenreported. (provided by RefSeq)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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