Rat CXCL1/CINC-1 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils.

We have publications tested in 2 confirmed species: Mouse, Rat.

Showing Publications 1 - 10 of 23. Show All 23 Publications. Collapse Publications.

Publications using RCN100	Applications	Species
AH Kadam, K Kandasamy, T Buss, B Cederstrom, C Yang, S Narayanapi, J Rodriguez, MD Levin, J Koziol, B Olenyuk, Z Borok, A Chrastina, JE Schnitzer Targeting caveolae to pump bispecific antibody to TGF-beta into diseased lungs enables ultra-low dose therapeutic efficacy PLoS ONE, 2022-11-22;17(11):e0276462. 2022-11-22 [PMID: 36413536] (Rat)		Rat
C Nishida, H Izumi, T Tomonaga, KY Wang, H Higashi, JI Takeshita, R Ono, K Sumiya, S Fujii, Y Hata, K Sakurai, Y Higashi, K Yamasaki, K Yatera, Y Morimoto Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation International Journal of Molecular Sciences, 2022-09-07;23(18):. 2022-09-07 [PMID: 36142256] (Rat)		Rat
MJ Allard, A Giraud, M Segura, G Sebire Sex-specific maternofetal innate immune responses triggered by group B Streptococci Sci Rep, 2019-06-13;9(1):8587. 2019-06-13 [PMID: 31197179] (Rat)		Rat
S Chakrabort, S Islam, S Saha, R Ain Dexamethasone-induced Intra-Uterine Growth Restriction impacts NOSTRIN and its downstream effector genes in the rat mesometrial uterus Sci Rep, 2018-05-29;8(1):8342. 2018-05-29 [PMID: 29844445] (Rat)		Rat
DY Liang, X Shi, P Liu, Y Sun, P Sahbaie, WW Li, DC Yeomans, JD Clark [EXPRESS] The Chemokine Receptor CXCR2 Supports Nociceptive Sensitization after Traumatic Brain Injury Mol Pain, 2017-01-01;13(0):1744806917730. 2017-01-01 [PMID: 28845733] (Rat)		Rat
C Vaamonde-G, J Loureiro, MN Valcárcel-, RR Riveiro-Na, O Ramil-Góme, L Hermida-Ca, A Centeno, R Meijide-Fa, FJ Blanco, MJ López-Arma The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint BMC Musculoskelet Disord, 2017-06-12;18(1):254. 2017-06-12 [PMID: 28606072] (Rat)		Rat
T Tomonaga, H Izumi, Y Yoshiura, T Myojo, T Oyabu, BW Lee, T Okada, Y Li, K Kawai, T Higashi, Y Morimoto Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives Biomed Res Int, 2017-01-16;2017(0):4245309. 2017-01-16 [PMID: 28191462] (Mouse)		Mouse
Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin D, Nakamura K, Honda M, Inoue K, Saito M Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat. PLoS ONE, 2015-08-26;10(8):e0133798. 2015-08-26 [PMID: 26308715] (Rat)		Rat
Boittin F, Denis J, Mayol J, Martigne P, Raffin F, Coulon D, Grenier N, Drouet M, Herodin F The extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure. PLoS ONE, 2015-04-02;10(4):e0122900. 2015-04-02 [PMID: 25836679] (Rat)		Rat
Burke S, Lu D, Sparer T, Masi T, Goff M, Karlstad M, Collier J NF-kappaB and STAT1 control CXCL1 and CXCL2 gene transcription. Am J Physiol Endocrinol Metab, 2013-11-26;306(2):E131-49. 2013-11-26 [PMID: 24280128] (Rat)		Rat
Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. J Biol Chem, 2013-02-28;288(15):10684-91. 2013-02-28 [PMID: 23449982] (Rat)		Rat
Wohlauer M, Moore E, Silliman C, Fragoso M, Gamboni F, Harr J, Accurso F, Wright F, Haenel J, Fullerton D, Banerjee A Nebulized hypertonic saline attenuates acute lung injury following trauma and hemorrhagic shock via inhibition of matrix metalloproteinase-13. Crit Care Med, 2012-09-01;40(9):2647-53. 2012-09-01 [PMID: 22732292] (Rat)		Rat
Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha. J. Biol. Chem., 2010-11-08;286(2):961-75. 2010-11-08 [PMID: 21059659] (Rat)		Rat
Sydlik U, Gallitz I, Albrecht C, Abel J, Krutmann J, Unfried K The compatible solute ectoine protects against nanoparticle-induced neutrophilic lung inflammation. Am. J. Respir. Crit. Care Med., 2009-03-26;180(1):29-35. 2009-03-26 [PMID: 19324973] (Rat)		Rat
Yang S, Hu S, Chen J, Choudhry MA, Rue LW, Bland KI, Chaudry IH Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses. J. Leukoc. Biol., 2009-02-24;85(6):1015-26. 2009-02-24 [PMID: 19244165] (Rat)		Rat
Kelher MR, Masuno T, Moore EE, Damle S, Meng X, Song Y, Liang X, Niedzinski J, Geier SS, Khan SY, Gamboni-Robertson F, Silliman CC Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model. Blood, 2009-01-08;113(9):2079-87. 2009-01-08 [PMID: 19131548] (Rat)		Rat
Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. Crit. Care Med., 2008-06-01;36(6):1846-54. 2008-06-01 [PMID: 18496381] (Rat)		Rat
Yu HP, Hsieh YC, Suzuki T, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. J. Leukoc. Biol., 2007-06-22;82(3):774-80. 2007-06-22 [PMID: 17586659] (Rat)		Rat
Nowak K, Weih S, Metzger R, Albrecht RF, Post S, Hohenberger P, Gebhard MM, Danilov SM Immunotargeting of catalase to lung endothelium via anti-angiotensin-converting enzyme antibodies attenuates ischemia-reperfusion injury of the lung in vivo. Am. J. Physiol. Lung Cell Mol. Physiol., 2007-04-13;293(1):L162-9. 2007-04-13 [PMID: 17435080] (Rat)		Rat
Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage. J. Mol. Cell. Cardiol., 2006-12-16;42(3):620-30. 2006-12-16 [PMID: 17313958] (Rat)		Rat
Laragione T, Yarlett NC, Brenner M, Mello A, Sherry B, Miller EJ, Metz CN, Gulko PS The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide. J. Immunol., 2007-02-15;178(4):2344-51. 2007-02-15 [PMID: 17277140] (Rat)		Rat
Yu HP, Yang S, Hsieh YC, Choudhry MA, Bland KI, Chaudry IH Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1. Am. J. Physiol. Lung Cell Mol. Physiol., 2006-03-23;291(3):L400-6. 2006-03-23 [PMID: 16556724] (Rat)		Rat
Yang S, Hu S, Hsieh YC, Choudhry MA, Rue LW, Bland KI, Chaudry IH Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage. J. Mol. Cell. Cardiol., 2006-02-24;40(4):570-9. 2006-02-24 [PMID: 16499925] (Rat)		Rat
Show All 23 Publications. Collapse Publications.

Array RCN100

• CXCL1/GRO alpha/KC/CINC-1 Antibodies
• CXCL1/GRO alpha/KC/CINC-1 ELISA Kit
• CXCL1/GRO alpha/KC/CINC-1 Proteins
• CXCL1/GRO alpha/KC/CINC-1 Proteins and Enzymes
• CXCL1/GRO alpha/KC/CINC-1 ELISAs