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PTEN Antibody (217702R) [Allophycocyanin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, KO
Clone
217702R
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC847RU-100UG
Alexa Fluor 405
IC847RV-100UG
Alexa Fluor 488
IC847RG-100UG
Alexa Fluor 532
FAB847RX
Alexa Fluor 594
IC847RT-100UG
Alexa Fluor 647
IC847RR-100UG
Alexa Fluor 700
IC847RN-100UG
Alexa Fluor 750
IC847RS-100UG
Biotin
FAB847RB
DyLight 350
FAB847RD
DyLight 405
FAB847RE
DyLight 488
FAB847RK
DyLight 550
FAB847RL
DyLight 594
FAB847RM
DyLight 650
FAB847RW
DyLight 680
FAB847RY
DyLight 755
FAB847RZ
FITC
FAB847RF
HRP
FAB847RH
Janelia Fluor 549
FAB847RI
Janelia Fluor 646
FAB847RJ
PE
FAB847RP
PerCP
FAB847RC
Unconjugated
MAB847R-100
mFluor Violet 450 SE
FAB847RMFV450
mFluor Violet 500 SE
FAB847RMFV500
mFluor Violet 610 SE
FAB847RMFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB847R-100
Carrier Free
MAB847R-100
Carrier Free
MAB847R-SP
Carrier Free
IC847RU-100UG
Carrier Free
IC847RR-100UG
Carrier Free
IC847RS-100UG
Carrier Free
IC847RG-100UG
Carrier Free
IC847RT-100UG
Carrier Free
IC847RN-100UG
Carrier Free
IC847RV-100UG
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PTEN Antibody (217702R) [Allophycocyanin] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
E. coli-derived recombinant human PTEN
Thr2-Val403
Accession # P60484
Specificity
Detects human PTEN in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Alternate Names for PTEN Antibody (217702R) [Allophycocyanin]

  • BZS
  • EC 3.1.3.16,10q23del
  • EC 3.1.3.48
  • EC 3.1.3.67
  • GLM2
  • MMAC1 phosphatase and tensin homolog deleted on chromosome 10
  • MMAC1
  • MMAC1MGC11227
  • Mutated in multiple advanced cancers 1
  • phosphatase and tensin homologDEC
  • phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN
  • PTEN
  • PTEN1
  • TEP1MHAM

Background

PTEN is a protein tyrosine phosphatase that acts as a tumor suppressor, as a lipid phosphatase that dephosphorylates the D3 position of phosphatidylinositol 3,4,5-trisphosphate and as an antagonist of the PI3k/AKT signaling pathway (1-3). PTEN structural domains includes an N-terminal phosphatase domain, a lipid binding C2 domain and a 50-amino acid C-terminal tail that contains a PD biding sequence (5). Phosporylation of the tail of the protein will suppress its activity and modify its conformation to a

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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