![Western Blot: Presenilin-1 Antibody [NBP1-33611] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE; antibody diluted at 1:1000.](http://images.novusbio.com/fullsize/Presenilin-1-Antibody-Western-Blot-NBP1-33611-img0007.jpg "Western Blot: Presenilin-1 Antibody [NBP1-33611] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE; antibody diluted at 1:1000.")
| Reactivity | Hu, Mu, RMSpecies Glossary |
| Applications | WB, ICC/IF, IHC |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugate | Unconjugated |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Presenilin-1. The exact sequence is proprietary. |
| Localization | Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein, Cell surface |
| Predicted Species | Rhesus Macaque (100%). Backed by our 100% Guarantee. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
| Gene | PSEN1 |
| Purity | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Theoretical MW | 53 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Buffer | 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol |
| Preservative | 0.01% Thimerosal |
| Purity | Antigen Affinity-purified |
![Western Blot beta-Catenin Antibody [Unconjugated]](https://images.novusbio.com/images2/beta-Catenin_AF1329_Western_Blot_5100.jpg)
![Chromatin Immunoprecipitation (ChIP) beta-Catenin Antibody [Unconjugated]](https://images.novusbio.com/images2/beta-Catenin_AF1329_Chromatin_Immunoprecipitation_11251.jpg)
![Simple Western beta-Catenin Antibody [Unconjugated]](https://images.novusbio.com/images2/betaCatenin_AF1329_Simple_Western_17134.jpg)
Secondary Antibodies |
Isotype Controls |
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The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
| Gene Symbol | PSEN1 |
![Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded mouse brain. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.](http://images.novusbio.com/fullsize/Presenilin-1-Antibody-Immunohistochemistry-Paraffin-NBP1-33611-img0011.jpg "Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded mouse brain. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.")
![Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution.](http://images.novusbio.com/fullsize/Presenilin-1-Antibody-Immunohistochemistry-Paraffin-NBP1-33611-img0008.jpg "Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution.")
![Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded U87 xenograft. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.](http://images.novusbio.com/fullsize/Presenilin-1-Antibody-Immunohistochemistry-Paraffin-NBP1-33611-img0010.jpg "Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded U87 xenograft. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.")
![Immunocytochemistry/Immunofluorescence: Presenilin-1 Antibody [NBP1-33611] - HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Presenilin 1 stained by Presenilin 1 antibody [C1C2], Internal diluted at 1:500.Blue: Hoechst 33342 staining. Scale bar= 10 um.](http://images.novusbio.com/fullsize/antibody/nbp1-33611_rabbit-polyclonal-presenilin-1-antibody-immunocytochemistry-immunofluorescence-562023123542..jpg "Immunocytochemistry/Immunofluorescence: Presenilin-1 Antibody [NBP1-33611] - HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Presenilin 1 stained by Presenilin 1 antibody [C1C2], Internal diluted at 1:500.Blue: Hoechst 33342 staining. Scale bar= 10 um.")
![Western Blot: Presenilin-1 Antibody [NBP1-33611] - Wild-type (WT) and Presenilin 1 knockout (KO) HeLa cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Presenilin 1 antibody [C1C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](http://images.novusbio.com/fullsize/nbp1-33611_rabbit-polyclonal-presenilin-1-antibody-1610202419414521.jpg "Western Blot: Presenilin-1 Antibody [NBP1-33611] - Wild-type (WT) and Presenilin 1 knockout (KO) HeLa cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Presenilin 1 antibody [C1C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.")
![Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).](https://images.novusbio.com/images/Goat-anti-Rabbit-IgG-H+L-Secondary-Antibody-HRP-Western-Blot-NB7160-img0001.jpg "Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).")
![Flow Cytometry: Rabbit IgG Isotype Control [NBP2-24891] - Intracellular FACS analysis of mouse TLR6 polyclonal antibody (red), rabbit isotype control (green), RAW cells alone (shaded). Two micrograms of antibodies were used. Goat anti-rabbit FITC (Novus, 20302) was used as secondary.](https://images.novusbio.com/images/Rabbit--Mouse-IgG-Isotype-Control-Flow-Cytometry-NBP2-24891-img0001.jpg "Flow Cytometry: Rabbit IgG Isotype Control [NBP2-24891] - Intracellular FACS analysis of mouse TLR6 polyclonal antibody (red), rabbit isotype control (green), RAW cells alone (shaded). Two micrograms of antibodies were used. Goat anti-rabbit FITC (Novus, 20302) was used as secondary.")