Podoplanin Antibody

Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a 38 kDa membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: IF/IHC, IHC-P, WB.

Showing Publications 1 - 6 of 6.

Publications using NBP1-90211	Applications	Species
Francipane MG, Han B, Lagasse E Host Lymphotoxin-beta Receptor Signaling Is Crucial for Angiogenesis of Metanephric Tissue Transplanted into Lymphoid Sites Am. J. Pathol. 2019-10-01 [PMID: 31585070]
Drosos I, Pavlaki M, Ortega Carrillo MDP et al. Increased Lymphangiogenesis and Lymphangiogenic Growth Factor Expression in Perivascular Adipose Tissue of Patients with Coronary Artery Disease J Clin Med 2019-07-09 [PMID: 31324038] (IF/IHC, Human)	IF/IHC	Human
Otto M, Blatt S, Pabst A et al. Influence of buffy coat-derived putative endothelial progenitor cells on tumor growth and neovascularization in oral squamous cell carcinoma xenografts. Clin Oral Investig 2019-01-28 [PMID: 30693401] (IHC-P, Mouse)	IHC-P	Mouse
Antoine Louveau, Igor Smirnov, Timothy J. Keyes et al. Structural and functional features of central nervous system lymphatic vessels. Nature 2015-06-01 [PMID: 26030524] (IF/IHC, Mouse)	IF/IHC	Mouse
Lathen C, Zhang Y et al. ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease. Circulation 2014-09-30 [PMID: 25062690] (WB, Mouse)	WB	Mouse
Schito L, Rey S, Tafani M et al. Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells Proc Natl Acad Sci U S A 2012-10-02 [PMID: 23012449] (IF/IHC, Mouse)	IF/IHC	Mouse

Array NBP1-90211

• Podoplanin Antibodies
• Podoplanin ELISA Kits
• Podoplanin Lysates
• Podoplanin Proteins
• Podoplanin Proteins and Enzymes