PNR/NR2E3 Antibody (OTI3D4) [PE]

Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP2-73510PE

• PNR/NR2E3 Antibodies
• PNR/NR2E3 Lysates
• PNR/NR2E3 Protein