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PNR/NR2E3 Antibody (OTI3D4) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
OTI3D4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

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PNR/NR2E3 Antibody (OTI3D4) [DyLight 488] Summary

Immunogen
Full length recombinant protein of human PNR/NR2E3 (NP_057430) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NR2E3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PNR/NR2E3 Antibody (OTI3D4) [DyLight 488]

  • NR2E3
  • Nuclear receptor subfamily 2 group E member 3
  • nuclear receptor subfamily 2, group E, member 3
  • photoreceptor-specific nuclear receptor
  • PNR
  • PNRESCS
  • rd7
  • Retina-specific nuclear receptor
  • RNR
  • RP37MGC49976

Background

Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NR2E3