Thymidylate Synthase Antibody (HL1236) - Azide and BSA Free Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Recombinant protein encompassing a sequence within the center region of human Thymidylate Synthase. The exact sequence is proprietary. |
Predicted Species |
Porcine (95%), Chimpanzee (99%), Rhesus Macaque (98%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
TYMS |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Western Blot 1:500-1:3000
|
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (86%), Xenopus (84%).
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
No Preservative |
Purity |
Protein A purified |
Alternate Names for Thymidylate Synthase Antibody (HL1236) - Azide and BSA Free
Background
Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for Thymidylate Synthase Antibody (NBP3-25721) (0)
Secondary Antibodies
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