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Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP1-87466] - Staining in human cerebral cortex and pancreas tissues using anti-CHRM1 antibody. ...read more
Immunocytochemistry/ Immunofluorescence: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP1-87466] - Staining of dissociated rat hippocampal culture. Image submitted by a verified customer review.
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP1-87466] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP1-87466] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHRM1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence Validated from a verified customer review.
  • Immunohistochemistry Free-Floating Reported in scientific literature (PMID: 31785263).
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Frozen Reported in scientific literature (PMID: 24658304).
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot Reported in scientific literature (PMID: 24658304).
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Muscarinic Acetylcholine Receptor M1/CHRM1 Protein (NBP1-87466PEP)
Reviewed Applications
Read 1 Review rated 4
using
NBP1-87466 in the following applications:

Publications
Read Publications using
NBP1-87466 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 31785263). Use in Rat reported in scientific literature (PMID:31785263).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

  • cholinergic receptor, muscarinic 1
  • CHRM1
  • HM1
  • M1
  • M1R
  • mAChR M1
  • MGC30125
  • muscarinic acetylcholine receptor M1

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody (NBP1-87466)(5)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ICC/IF, IHC-Fr, IHC-FrFl, Western Blot.


Filter By Application
ICC/IF
(1)
IHC-Fr
(1)
IHC-FrFl
(1)
Western Blot
(1)
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Human
(2)
Mouse
(1)
Rat
(1)
All Species

Review for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody (NBP1-87466) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Rat.

Reviews using NBP1-87466:
Filter by Applications
ICC
(1)
All Applications
Filter by Species
Rat
(1)
All Species
Images Ratings Applications Species Date Details
Immunocytochemistry Muscarinic Acetylcholine Receptor M1/CHRM1 NBP1-87466
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4
reviewed by:
Bryan Tinsley
ICC Rat 08/27/2014
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Summary

ApplicationImmunocytochemistry
SpeciesRat

Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody (NBP1-87466) (0)

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Secondary Antibodies

 

Isotype Controls

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Recent Reviews

4
5
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4
1
3
0
2
0
1
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Bryan Tinsley
08/27/2014
Application: ICC
Species: Rat

Bioinformatics

Gene Symbol CHRM1