Species: Hu
Applications: WB, IHC, ELISA
Host: Mouse Monoclonal
Species: Hu, Mu, Po, Bt, Bv, Eq, Ha, Pm, Pm, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
Bioinformatics
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
10002 |
| Alternate Names |
- Nuclear receptor subfamily 2 group E member 3
- nuclear receptor subfamily 2, group E, member 3
- photoreceptor-specific nuclear receptor
- PNRESCS
- rd7
- Retina-specific nuclear receptor
- RNR
- RP37MGC49976
|
Research Areas for PNR/NR2E3
Find related products by research area and learn more about each of the different research areas below.
GPCRVision
