PDGFR alpha Antibody (OTI1C10)

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.

Showing Publication 1 - 1 of 1.

Publication using NBP2-46357	Applications	Species
Suehara Y, Alex D, Bowman AS et al. Clinical genomic sequencing of pediatric and adult osteosarcoma reveals distinct molecular subsets with potentially targetable alterations Clin. Cancer Res. 2019-06-07 [PMID: 31175097] (IF/IHC, Human)	IF/IHC	Human

Array NBP2-46357

• PDGFR alpha Antibodies
• PDGFR alpha Antibody Pair
• PDGFR alpha Lysate
• PDGFR alpha Protein
• PDGFR alpha ELISAs
• PDGFR alpha Proteins and Enzymes