PDE6 beta Antibody - BSA Free

Images

 
Western Blot: PDE6 beta Antibody [NBP2-95225] - Analysis of extracts of various cell lines, using PDE6 beta at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: ...read more
Immunohistochemistry-Paraffin: PDE6 beta Antibody [NBP2-95225] - Paraffin-embedded rat retina using PDE6 beta .
Immunohistochemistry-Paraffin: PDE6 beta Antibody [NBP2-95225] - Paraffin-embedded mouse retina using PDE6 beta .

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

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Catalog# & Formulation Size Price

PDE6 beta Antibody - BSA Free Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NP_001138763.1). MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDCDSLRDLCQVEESTALLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGKDVVAVI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDE6B
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for PDE6 beta Antibody - BSA Free

  • CSNB3
  • EC 3.1.4
  • EC 3.1.4.35
  • GMP-PDE beta
  • PDE6 beta
  • PDE6B
  • PDEB
  • PDEBrod cGMP-phosphodiesterase beta-subunit
  • phosphodiesterase 6B, cGMP-specific, rod, beta
  • rd1
  • rod cGMP-specific 3'-5'-cyclic phosphodiesterase subunit beta
  • RP40CSNBAD2

Background

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PDE6 beta Antibody (NBP2-95225) (0)

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PDE6B