Independent Antibodies: Immunohistochemistry-Paraffin: PDE6A Antibody [NBP1-87312] - Staining of human cerebral cortex, endometrium, eye, retina and liver using Anti-PDE6A antibody NBP1-87312 (A) shows similar ...read more
Western Blot: PDE6A Antibody [NBP1-87312] - Analysis in control (vector only transfected HEK293T lysate) and PDE6A over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: PDE6A Antibody [NBP1-87312] - Staining of human endometrium shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: PDE6A Antibody [NBP1-87312] - Staining of human retina shows moderate cytoplasmic positivity in rods.
Immunohistochemistry-Paraffin: PDE6A Antibody [NBP1-87312] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: PDE6A Antibody [NBP1-87312] - Staining of human liver shows no positivity in hepatocytes as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: TLMESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHN
Predicted Species
Rat (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDE6A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use in Monkey reported in scientific literature (PMID:35024589). Mouse reactivity reported in scientific literature (PMID: 26188004).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for PDE6A Antibody
CGPR-A
EC 3.1.4
EC 3.1.4.35
GMP-PDE alpha
PDE V-B1
PDE6A
PDEA
PDEAcGMP phosphodiesterase alpha subunit
phosphodiesterase 6A, cGMP-specific, rod, alpha
rod cGMP-specific 3'-5'-cyclic phosphodiesterase subunit alpha
rod photoreceptor cGMP phosphodiesterase alpha subunit
RP43
Background
Phosphodiesterase 6A, a catalytic subunit of the photoreceptor phosphodiesterase, has been shown to affect functioning of eye retina as the alpha subunit of the heterotetrameric rod photoreceptor. Mutations in PDE6A have been identified as a cause of autosomal recessive retinitis pigmentosa.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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