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p67phox/NOXA2 Antibody (001) [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      NBP2-90316JF585
    • Availability
      Product Discontinued

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p67phox/NOXA2 Antibody (001) [Janelia Fluor® 585] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human p67phox/NOXA2 (Accession#: AAH01606.1; Met1-Val526).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
NCF2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for p67phox/NOXA2 Antibody (001) [Janelia Fluor® 585]

  • autosomal 2
  • NADPH oxidase activator 2
  • NCF2
  • NCF-2
  • neutrophil cytosol factor 2
  • neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal2)
  • neutrophil cytosolic factor 2
  • NOXA2
  • NOXA2FLJ93058
  • p67phox
  • p67-phox

Background

NOXA2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NCF2