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Recombinant Human p15INK4b/CDKN2B GST (N-Term) Protein

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12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, MA, AP

Order Details

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Recombinant Human p15INK4b/CDKN2B GST (N-Term) Protein Summary

Description
A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-138 of Human CDKN2B

Source: Wheat Germ (in vitro)

Amino Acid Sequence: MREENKGIPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEERGHRDVAGYLRTATGD

Preparation
Method
in vitro wheat germ expression system
Details of Functionality
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
Source
Wheat germ
Protein/Peptide Type
Recombinant Protein
Gene
CDKN2B
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • Western Blot
Theoretical MW
40.92 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human p15INK4b/CDKN2B GST (N-Term) Protein

  • CDK4I
  • CDKN2B
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
  • cyclin-dependent kinases 4 and 6 binding protein
  • INK4BCDK4B inhibitor
  • MTS2
  • MTS-2
  • MTS2CDK inhibitory protein
  • Multiple tumor suppressor 2
  • p14_CDK inhibitor
  • p14_INK4B
  • p14-INK4b
  • p15 CDK inhibitor
  • p15_INK4B
  • P15cyclin-dependent kinase 4 inhibitor B
  • p15INK4b
  • p15-INK4b
  • TP15

Background

sCDKN2B( AAH14469, 1 a.a. - 139 a.a.) recombinant protein with GST.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CDKN2B