P-Cadherin Antibody

CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 3 applications: ICC/IF, IF/IHC, IHC-P.

Showing Publications 1 - 5 of 5.

Publications using NBP1-59222	Applications	Species
Neupane S, Sohn WJ, Gwon GJ et al. The role of APCDD1 in epithelial rearrangement in tooth morphogenesis. Histochem Cell Biol 2015-10-01 [PMID: 26170146]
Lindfors S Molecular mechanisms of podocyte injury: focus on adiponectin signalling in obesity and type 2 diabetes Thesis 2023-01-01
Yang CC, Sung PH, Chen KH et al. Valsartan- and melatonin-supported adipose-derived mesenchymal stem cells preserve renal function in chronic kidney disease rat through upregulation of prion protein participated in promoting PI3K-Akt-mTOR signaling and cell proliferation Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021-12-20 [PMID: 34923336] (ICC/IF, IF/IHC, Rat)	ICC/IF, IF/IHC	Rat
Yang CC, Sung PH, Chen CH Et al. Additional benefit of induced pluripotent stem cell-derived mesenchymal stem cell therapy on sepsis syndrome-associated acute kidney injury in rat treated with antibiotic Stem cell research & therapy 2021-10-07 [PMID: 34620235] (IHC-P, Rat)	IHC-P	Rat
Cheung KJ, Gabrielson E, Werb Z, Ewald AJ. Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program. Cell 2013-12-19 [PMID: 24332913] (ICC/IF, Mouse)	ICC/IF	Mouse

Array NBP1-59222

• P-Cadherin Antibodies
• P-Cadherin ELISA Kits
• P-Cadherin Lysate
• P-Cadherin Protein
• P-Cadherin ELISA
• P-Cadherin Proteins and Enzymes