Olig2 Antibody - Azide and BSA Free

Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. (Arnett et al., 2004) From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 8 applications: ICC/IF, IF/IHC, IHC, IHC-Fr, IHC-FrFl, IHC-P, Immunohistochemistry, WB.

Showing Publications 1 - 10 of 35. Show All 35 Publications. Collapse Publications.

Publications using NBP1-28667	Applications	Species
Huang CW, Lee KY, Lin PT et al. Muscleblind-Like 2 knockout shifts adducin 1 isoform expression and alters dendritic spine dynamics of cortical neurons during brain development Neuropathology and applied neurobiology 2023-02-10 [PMID: 36765387] (IHC, Mouse)	IHC	Mouse
Larrigan S, Joshi S, Mattar P Divergent phenotypes in germline versus conditional mutant mouse models of Sifrim-Hitz-Weiss Syndrome bioRxiv 2023-02-16 (IHC-Fr, Mouse)	IHC-Fr	Mouse
Milstead R, Link C, Xu Z, Hoeffer C Molecular Signaling and Neural Cell Type Expression of Complex Brain Disorders Thesis 1905-07-13 (IHC-Fr, Mouse)	IHC-Fr	Mouse
Larrigan S, Joshi SV, Mattar P Divergent phenotypes in constitutive versus conditional mutant mouse models of Sifrim-Hitz-Weiss syndrome Human molecular genetics 2023-09-21 [PMID: 37738575]
Kim JT, Cho SM, Youn DH et al. Therapeutic effect of a hydrogel-based neural stem cell delivery sheet for mild traumatic brain injury Acta biomaterialia 2023-06-23 [PMID: 37356785] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Zhai J, Xu Y, Wan H et al. Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture Cell 2023-05-11 [PMID: 37172562]
Milstead R, Link C, Xu Z, Hoeffer C Molecular Signaling and Neural Cell Type Expression of Complex Brain Disorders Thesis Jul 13 1905 (IHC-Fr, Mouse)	IHC-Fr	Mouse
Milstead RA, Link CD, Xu Z, Hoeffer CA TDP-43 knockdown in mouse model of ALS leads to dsRNA deposition, gliosis, and neurodegeneration in the spinal cord Cerebral cortex (New York, N.Y. : 1991) 2022-11-28 [PMID: 36443249]
Xu L, Nirwane A, Xu T et al. Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2 Cell reports 2022-11-22 [PMID: 36417884] (IF/IHC, Mouse)	IF/IHC	Mouse
Ma L, Liang C, Wang J et al. Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors Human molecular genetics 2022-11-02 [PMID: 36322143] (IF/IHC, Mouse)	IF/IHC	Mouse
Nirwane A, Yao Y SMAlow/undetectable pericytes differentiate into microglia- and macrophage-like cells in ischemic brain Cellular and molecular life sciences : CMLS 2022-04-28 [PMID: 35482211]
Shao E, Chang CW, Li Z et al. TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model Science translational medicine 2022-04-27 [PMID: 35476595] (IHC-FrFl, Mouse)	IHC-FrFl	Mouse
Kim D, Kim S, Sung A et al. Autologous treatment for ALS with implication for broad neuroprotection Translational neurodegeneration 2022-03-11 [PMID: 35272709] (ICC/IF, Human)	ICC/IF	Human
Hao W, Luo Q, Menger M et al. Treatment With CD52 Antibody Protects Neurons in Experimental Autoimmune Encephalomyelitis Mice During the Recovering Phase Frontiers in Immunology 2021-12-16 [PMID: 34975892] (IHC-P, Mouse)	IHC-P	Mouse
Suter T, Wang J, Meng H, He Z Utilizing mouse optic nerve crush to examine CNS remyelination STAR Protocols 2021-09-01 [PMID: 34786561]
Satake T Epstein-Barr virus-based plasmid enables inheritable transgene expression in mouse cerebral cortex PLOS ONE 2021-09-30 [PMID: 34591902]
MOROKI T, MATSUO S, HATAKEYAMA H et al. Databases for technical aspects of immunohistochemistry-2021 update Journal of Toxicologic Pathology 2021-02-24 [PMID: 33976473] (IF/IHC, Mouse)	IF/IHC	Mouse
Hung TH, Liu YC, Wu CH et al. Antenatal low-intensity pulsed ultrasound reduces neurobehavioral deficits and brain injury following dexamethasone-induced intrauterine growth restriction Brain pathology (Zurich, Switzerland) 2021-05-07 [PMID: 33960564]
Bartosovic M, Kabbe M, Castelo-Branco G Single-cell CUT and Tag profiles histone modifications and transcription factors in complex tissues Nature biotechnology 2021-04-12 [PMID: 33846645]
Yazdankhah M, Ghosh S, Shang P, et al. BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes Autophagy 2021-01-19 [PMID: 33404293] (ICC/IF, Rat)	ICC/IF	Rat
Barodia, S K, McMeekin, L J Et al. PINK1 phosphorylates ubiquitin predominantly in astrocytes. NPJ Parkinsons Dis 2019-12-11 [PMID: 33298973] (WB, Mouse)	WB	Mouse
Wang J, He X, Meng H et al. Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia Neuron 2020-10-23 [PMID: 33108748]
Da Hee Jung, Malk Eun Pak, Hong Ju Lee, Sung Min Ahn, Young Ju Yun, Yong-Il Shin, Hwa Kyoung Shin, Seo-Yeon Lee, Byung Tae Choi Electroacupuncture on the Scalp over the Motor Cortex Ameliorates Behavioral Deficits Following Neonatal Hypoxia-Ischemia in Rats via the Activation of Neural Stem Cells Life 2020-10-14 [PMID: 33066563]
Cavaccini A, Durkee C, Kofuji P et al. Astrocyte signaling gates long-term depression at corticostriatal synapses of the direct pathway J. Neurosci. 2020-06-15 [PMID: 32541069]
Zhang H, Chen W, Tan Z et al. A role of low-density lipoprotein receptor-related protein 4 (LRP4) in astrocytic A beta clearance J. Neurosci. 2020-05-26 [PMID: 32457076] (WB, Human)	WB	Human
Barodia SK, McMeekin LJ, Creed RB et al. PINK1 phosphorylates ubiquitin predominantly in astrocytes NPJ Parkinsons Dis 2019-12-11 [PMID: 31840043] (WB, Rat)	WB	Rat
Epperly M W, Fisher R et al. Amelioration of Amyotrophic Lateral Sclerosis in SOD1G93A Mice by M2 Microglia from Transplanted Marrow. In Vivo 2019-04-28 [PMID: 31028184] (ICC/IF, Mouse)	ICC/IF	Mouse
Diana C. Lozano, Tiffany E. Choe, William O. Cepurna, John C. Morrison, Elaine C. Johnson Early Optic Nerve Head Glial Proliferation and Jak-Stat Pathway Activation in Chronic Experimental Glaucoma Investigative Ophthalmology & Visual Science 2019-03-01 [PMID: 30835784]
Gotoh H, Wood WM, Patel kD et al. NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer. Glia. 2018-10-10 [PMID: 30306660] (Mouse)		Mouse
Janardhan KS, Jensen H, Clayton NP, Herbert RA Immunohistochemistry in Investigative and Toxicologic Pathology Toxicol Pathol. 2018-07-01 [PMID: 29966501] (IF/IHC, Mouse) Details: Citation used the HRP format of this antibody.	IF/IHC	Mouse
Sumiyoshi K, Koso H, Watanabe S. Spontaneous development of intratumoral heterogeneity in a transposon-induced mouse model of glioma Cancer Sci. 2018-05-01 [PMID: 29575648] (IF/IHC, Mouse)	IF/IHC	Mouse
Zuo H, Wood WM, Sherafat A, Hill RA. Age-dependent decline in fate switch from NG2 cells to astrocytes after Olig2 deletion. J. Neurosci. 2018-01-30 [PMID: 29382710] (Mouse)		Mouse
Yu MS, Tanese N. Huntingtin is required for neural but not cardiac/pancreatic progenitor differentiation of mouse embryonic stem cells in vitro. Front Cell Neurosci. 2017-02-21 [PMID: 28270748] (WB, Mouse)	WB	Mouse
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol 2017-01-01 [PMID: 28190929]
Kolenda-Roberts HM, Harris N, Singletary E, Hardisty JF. Immunohistochemical Characterization of Spontaneous and Acrylonitrile-induced Brain Tumors in the Rat Toxicol Pathol 2013-01-01 [PMID: 22821367] (IF/IHC, Rat)	IF/IHC	Rat
Show All 35 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Abhijit Nirwane	IHC-Fr	Mouse	04/17/2019	View Summary Application Immunohistochemistry-Frozen Sample Tested Mouse brain Species Mouse Lot DF116y Comments Comments Mice brain slices
	4 reviewed by: Kazuya Oikawa	IHC-Fr	Feline	02/06/2019	View Summary Application Immunohistochemistry-Frozen Sample Tested Optic nerve Species Feline Lot DF1217g
Enlarge	5 reviewed by: Verified Customer	Immunohistochemistry-microslice section	Mouse	08/07/2017	View Summary Application Other Sample Tested Brain (cerebral cortex) Species Mouse Lot DF116y Comments Comments Anti-Olig2 was used at a 1/800 dilution.
	5 reviewed by: Nancy Harris	IHC-P	Rat	02/26/2013	View Summary Application Immunohistochemistry-Paraffin Sample Tested Rat brain tumors Species Rat Lot DF1009R

Array NBP1-28667

• Olig2 Antibodies
• Olig2 Lysate
• Olig2 Proteins